Evolution of glutamatergic signaling and synapses

LL Moroz, MA Nikitin, PG Poličar, AB Kohn… - …, 2021 - Elsevier
Glutamate (Glu) is the primary excitatory transmitter in the mammalian brain. But, we know
little about the evolutionary history of this adaptation, including the selection of l-glutamate …

Proteome-wide 3D structure prediction provides insights into the ancestral metabolism of ancient archaea and bacteria

W Zhao, B Zhong, L Zheng, P Tan, Y Wang… - Nature …, 2022 - nature.com
Ancestral metabolism has remained controversial due to a lack of evidence beyond
sequence-based reconstructions. Although prebiotic chemists have provided hints that …