DNA methyltransferases: from evolution to clinical applications

VM Del Castillo Falconi, K Torres-Arciga… - International journal of …, 2022 - mdpi.com
DNA methylation is an epigenetic mark that living beings have used in different
environments. The MTases family catalyzes DNA methylation. This process is conserved …

Drugs targeting epigenetic modifications and plausible therapeutic strategies against colorectal cancer

S Patnaik, Anupriya - Frontiers in Pharmacology, 2019 - frontiersin.org
Genetic variations along with epigenetic modifications of DNA are involved in colorectal
cancer (CRC) development and progression. CRC is the fourth leading cause of cancer …

Developments and opportunities in fungal strain engineering for the production of novel enzymes and enzyme cocktails for plant biomass degradation

RS Kun, ACS Gomes, KS Hildén, SS Cerezo… - Biotechnology …, 2019 - Elsevier
Fungal strain engineering is commonly used in many areas of biotechnology, including the
production of plant biomass degrading enzymes. Its aim varies from the production of …

Epigenetic manipulation of filamentous fungi for biotechnological applications: a systematic review

MJ Poças-Fonseca, CG Cabral… - Biotechnology letters, 2020 - Springer
The study of the epigenetic regulation of gene function has reached pivotal importance in life
sciences in the last decades. The mechanisms and effects of processes such as DNA …

Cellulose-degrading enzymes: key players in biorefinery development

JR Dos Santos, LR de Souza Moreira, EXF Filho - Biologia, 2023 - Springer
Saccharification recalcitrance significantly limits the conversion of lignocellulosic biomass to
valuable end products. The intricate arrangement between cell wall matrix polysaccharides …

[HTML][HTML] Improvement of Monacolin K and Pigment Production in Monascus by 5-Azacytidine

C Zhang, H Wang, Q Sun, A Ablimit, H Dong, C Wang… - Journal of Fungi, 2024 - mdpi.com
Monascus species are known to produce various secondary metabolites with polyketide
structures, including Monacolins, pigments, and citrinin. This study investigates the effects of …

Nucleic acid demethylase MpAlkB1 regulates the growth, development, and secondary metabolite biosynthesis in Monascus purpureus

T Qiu, L Zeng, Y Chen, Y Yang - World Journal of Microbiology and …, 2024 - Springer
Nucleic acid demethylases of α-ketoglutarate-dependent dioxygenase (AlkB) family can
reversibly erase methyl adducts from nucleobases, thus dynamically regulating the …

Análise do efeito do tratamento fotodinâmico mediada por nanoemulsão contendo cloreto de alumínio-ftalocianina sobre a produção de hidrolases de Humicola …

CG Cabral - 2020 - icts.unb.br
O tratamento fotodinâmica (TFD) consiste na foto-oxidação de um composto biológico
mediada por um fotossensibilizante que será exposto a luz de comprimento de onda …