Future perspectives of uveal melanoma blood based biomarkers

AB Beasley, FK Chen, TW Isaacs, ES Gray - British Journal of Cancer, 2022 - nature.com
Uveal melanoma (UM) is the most common primary intraocular malignancy affecting adults.
Despite successful local treatment of the primary tumour, metastatic disease develops in up …

The prognostic value of circulating tumor cells in patients with melanoma: a systematic review and meta-analysis

S Mocellin, D Hoon, A Ambrosi, D Nitti, CR Rossi - Clinical cancer research, 2006 - AACR
Background: The detection of circulating tumor cells (CTC) in patients with melanoma
represents an appealing prognostic tool, but no consensus exists on this topic. We aimed to …

Negative enrichment by immunomagnetic nanobeads for unbiased characterization of circulating tumor cells from peripheral blood of cancer patients

Z Liu, A Fusi, E Klopocki, A Schmittel, I Tinhofer… - Journal of translational …, 2011 - Springer
Background A limitation of positive selection strategies to enrich for circulating tumor cells
(CTCs) is that there might be CTCs with insufficient expression of the surface target marker …

Circulating serologic and molecular biomarkers in malignant melanoma

SR Palmer, LA Erickson, I Ichetovkin, DJ Knauer… - Mayo clinic …, 2011 - Elsevier
The worldwide incidence of malignant melanoma has been increasing during the past
decade and is a public health concern because this disease accounts for up to 90% of …

[HTML][HTML] Preliminary investigation of the clinical significance of detecting circulating tumor cells enriched from lung cancer patients

C Wu, H Hao, L Li, X Zhou, Z Guo, L Zhang… - Journal of thoracic …, 2009 - Elsevier
Background: Enumeration of circulating tumor cells (CTCs) may be valuable for lung cancer
treatment and monitoring cancer patient relapse. In the present study we report clinical …

Prognosis of non–small cell lung cancer patients by detecting circulating cancer cells in the peripheral blood with multiple marker genes

YP Sher, JY Shih, PC Yang, SR Roffler, YW Chu… - Clinical cancer …, 2005 - AACR
Purpose: Current lung cancer staging and prognosis methods are based on imaging
methods, which may not be sensitive enough for early and accurate detection of metastasis …

Prognostic relevance of occult nodal micrometastases and circulating tumor cells in colorectal cancer in a prospective multicenter trial

K Koyanagi, AJ Bilchik, S Saha, RR Turner… - Clinical Cancer …, 2008 - AACR
Purpose: Nodal micrometastasis and circulating tumor cells detected by multimarker
quantitative real-time reverse transcription-PCR (qRT-PCR) may have prognostic …

Circulating neoplastic-immune hybrid cells predict metastatic progression in uveal melanoma

MS Parappilly, Y Chin, RM Whalen, AN Anderson… - Cancers, 2022 - mdpi.com
Simple Summary Uveal melanoma is an aggressive cancer that begins in the eye, but often
spreads to distant organs when tumor cells enter the blood. Disease spreads in nearly half …

Pyrophosphorolysis-activated polymerization detects circulating tumor DNA in metastatic uveal melanoma

J Madic, S Piperno-Neumann, V Servois… - Clinical Cancer …, 2012 - AACR
Purpose: To develop a molecular tool to detect circulating tumor–derived DNA (ctDNA) in
the plasma from patients with uveal melanoma as a marker of tumor burden and monitor …

Liquid biopsy in uveal melanoma: are we there yet?

E Jin, JV Burnier - Ocular Oncology and Pathology, 2021 - karger.com
In the era of precision oncology, major strides are being made to use individual tumor
information for clinical decision-making. Differing from traditional biopsy methods, the …