Hydrogen/deuterium exchange (HDX) mass spectrometry (MS) has become a key technique
for monitoring structural and dynamic aspects of proteins in solution. This approach relies on …

Publisher Summary This chapter deals with the structure of the molten globules of various
globular proteins revealed by the recent experimental studies. Recent advances in …

▪ Abstract Mass spectrometry has provided a powerful method for monitoring hydrogen
exchange of protein backbone amides with deuterium from solvent. In comparison to …

Abstract I. Introduction 38 A. Protein Conformations and Dynamics 38 B. Protein‐Energy
Landscapes: The Folding Problem and Dynamics in the Native State 38 1. Protein …

Publisher Summary Nuclear magnetic resonance (NMR) is unique in being able to provide
detailed insights into the conformation of unfolded and partly folded proteins. This chapter …

Amide H/D exchange (HDX) mass spectrometry (MS) is widely used for protein structural
studies. Traditionally, this technique involves protein labeling in D2O, followed by acid …

Conformational changes and protein dynamics play an important role in the catalytic
efficiency of enzymes. Amide H/D exchange mass spectrometry (H/D exchange MS) is …

The direct linkage between folded structures of proteins and their function has increased the
need for high resolution structures. In addition, there is a need for analytical methods for …

Mass spectrometry (MS) plays a central role in studies on protein structure and dynamics.
This review highlights some of the recent developments in this area, with focus on …

Life at the molecular level is a dynamic world, where the key players─ proteins,
oligonucleotides, lipids, and carbohydrates─ are in a perpetual state of structural flux …