Currently, pyroptosis has received more and more attention because of its association with
innate immunity and disease. The research scope of pyroptosis has expanded with the …

Almost all human diseases are strongly associated with inflammation, and a deep
understanding of the exact mechanism is helpful for treatment. The NLRP3 inflammasome …

The abundance of innate and adaptive immune cells that reside together with trillions of
beneficial commensal microorganisms in the mammalian gastrointestinal tract requires …

Intestinal phagocytes transport oral antigens and promote immune tolerance, but their role in
innate immune responses remains unclear. Here we found that intestinal phagocytes were …

The risk of onset of cancer is influenced by poorly controlled chronic inflammatory
processes. Inflammatory diseases related to cancer development include inflammatory …

Inflammasomes form as the result of the intracellular presence of danger-associated
molecular patterns and mediate the release of active IL-1β, which influences a variety of …

Colorectal cancer (CRC) is one of the most common digestive tract malignancies and
inflammation and gut microbiota are well-known key factors to influence CRC development …

Chronic inflammatory responses have long been observed to be associated with various
types of cancer and play decisive roles at different stages of cancer development …

Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-
associated (Cas) genes are present in many bacterial and archaeal genomes. Since the …

Pyroptosis, a type of inflammatory programmed cell death, is mediated by multiple
inflammasomes which can recognize danger signals and activate the secretion of pro …