There are numerous disorders of known or presumed neurologic origin that result in
excessive daytime sleepiness, collectively known as the central disorders of …

There are multiple disorders of neurodevelopment that present with co-occurring sleep
disturbances. Many of these neurodevelopmental disorders (NDD) include sleep …

Background In the last 20 years, substantial improvements have been made in the
diagnosis, treatment and management of patients with Prader-Willi syndrome (PWS). Few …

Abstract Context Prader-Willi syndrome (PWS) is a complex hypothalamic disorder,
combining hyperphagia, hypotonia, intellectual disability, and pituitary hormone …

Since the discovery of the histamine H 3 receptor in 1983, tremendous advances in the
pharmacological aspects of H 3 receptor antagonists/inverse agonists have been …

The American Academy of Sleep Medicine commissioned a task force of clinical experts in
pediatric sleep medicine to review published literature on performing the Multiple Sleep …

Idiopathic hypersomnia (IH) includes a clinical phenotype resembling narcolepsy (with
repeated, short restorative naps), and a phenotype with an excess of sleep, sleep …

Abstract Purpose of Review This paper reviews how sleep is impacted in patients with
Prader-Willi syndrome (PWS), focusing on sleep-related breathing disturbances and …

Clinical experience and a growing body of evidence suggest that sleep disturbances are
common in people with Prader-Willi syndrome (PWS). PWS is a rare neuroendocrine …

Prader–Willi syndrome (PWS) is recognized as the first example of genomic imprinting,
generally due to a de novo paternal 15q11-q13 deletion. PWS is considered the most …