Clinical application of immune repertoire sequencing in solid organ transplant

P Wong, DP Cina, KR Sherwood, F Fenninger… - Frontiers in …, 2023 - frontiersin.org
Background Measurement of T cell receptor (TCR) or B cell receptor (BCR) gene utilization
may be valuable in monitoring the dynamic changes in donor-reactive clonal populations …

[HTML][HTML] Optimum timing of antithymocyte globulin in relation to adoptive regulatory T cell therapy

M Muckenhuber, J Mucha, K Mengrelis, C How… - American Journal of …, 2023 - Elsevier
Reducing the recipient's T cell repertoire is considered to increase the efficacy of regulatory
T cell (Treg) therapy. This necessitates timing the administration of antithymocyte globulin …

Combination cell therapy leads to clonal deletion of donor-specific T cells in kidney transplant recipients

AF David, A Heinzel, M Kammer, C Aschauer… - …, 2024 - thelancet.com
Background Induction of donor-specific tolerance is a promising approach to achieve long-
term graft patency in transplantation with little to no maintenance immunosuppression …

T-cell receptor sequencing reveals selected donor-reactive CD8+ T cell clones resist antithymocyte globulin depletion after kidney transplantation

M Ningoo, P Cruz-Encarnación, C Khilnani… - American Journal of …, 2024 - Elsevier
High frequencies of donor-reactive memory T cells in the periphery of transplant candidates
prior to transplantation are linked to the development of posttransplant acute rejection …

Supplementary Table. Patient Characteristics

IDSA Race - amjtransplant.org
1 Supplementary Table. Patient Characteristics Page 1 1 Supplementary Table. Patient
Characteristics ID Sex Age Race Primary Kidney Disease Donor Sex Donor Age HLA …