The knowns and unknowns of SSRI treatment in young people with depression and anxiety: efficacy, predictors, and mechanisms of action
The use of SSRIs for the treatment of depression and anxiety in young people is increasing.
However, the effects of SSRIs in adolescence, a time when there are substantial changes in …
However, the effects of SSRIs in adolescence, a time when there are substantial changes in …
Personalized medicine and cognitive behavioral therapies for depression: Small effects, big problems, and bigger data
L Lorenzo-Luaces, A Peipert… - International Journal of …, 2021 - Springer
Cognitive-behavioral therapies (CBTs) are the most widely studied form of psychotherapy for
disorders like depression and anxiety. Nonetheless, there is heterogeneity in response to …
disorders like depression and anxiety. Nonetheless, there is heterogeneity in response to …
Predictors of treatment outcome of psychological therapies for common mental health problems (CMHP) in older adults: A systematic literature review
Identifying factors that impact psychological treatment outcomes in older people with
common mental health problems (CMHP) has important implications for supporting healthier …
common mental health problems (CMHP) has important implications for supporting healthier …
Circadian rhythm biomarker from wearable device data is related to concurrent antidepressant treatment response
Major depressive disorder (MDD) is associated with circadian rhythm disruption. Yet, no
circadian rhythm biomarkers have been clinically validated for assessing antidepressant …
circadian rhythm biomarkers have been clinically validated for assessing antidepressant …
The importance of transdiagnostic symptom level assessment to understanding prognosis for depressed adults: analysis of data from six randomised control trials
Background Depression is commonly perceived as a single underlying disease with a
number of potential treatment options. However, patients with major depression differ …
number of potential treatment options. However, patients with major depression differ …
The contribution of depressive 'disorder characteristics' to determinations of prognosis for adults with depression: an individual patient data meta-analysis
BackgroundThis study aimed to investigate general factors associated with prognosis
regardless of the type of treatment received, for adults with depression in primary care …
regardless of the type of treatment received, for adults with depression in primary care …
Ketamine-assisted psychotherapy in adolescents with multiple psychiatric diagnoses
PE Wolfson, J Andries, D Ahlers, M Whippo - Frontiers in Psychiatry, 2023 - frontiersin.org
Ketamine-assisted psychotherapy is a promising new treatment for a variety of mental
disorders of adolescence. There is currently an adolescent mental health crisis, with a high …
disorders of adolescence. There is currently an adolescent mental health crisis, with a high …
Predicting prognosis for adults with depression using individual symptom data: a comparison of modelling approaches
BackgroundThis study aimed to develop, validate and compare the performance of models
predicting post-treatment outcomes for depressed adults based on pre-treatment data …
predicting post-treatment outcomes for depressed adults based on pre-treatment data …
Why is it so hard to identify (consistent) predictors of treatment outcome in psychotherapy?–clinical and research perspectives
SEH Eilertsen, TH Eilertsen - BMC psychology, 2023 - Springer
Background Anxiety and depression are two of the most debilitating psychological disorders
worldwide today. Fortunately, effective treatments exist. However, a large proportion of …
worldwide today. Fortunately, effective treatments exist. However, a large proportion of …
Methods for quantifying the heterogeneity of psychopathology
Objectives Specifiers for a major depressive disorder (MDE) are supposed to reduce
diagnostic heterogeneity. However, recent literature challenges the idea that the atypical …
diagnostic heterogeneity. However, recent literature challenges the idea that the atypical …