Xanthones and cancer: from natural sources to mechanisms of action

LC Klein‐Júnior, A Campos, R Niero… - Chemistry & …, 2020 - Wiley Online Library
Xanthones are a class of heterocyclic natural products that have been widely studied for
their pharmacological potential. In fact, they have been serving as scaffolds for the design of …

Bioactive natural antivirals: An updated review of the available plants and isolated molecules

S Mohan, MM Elhassan Taha, HA Makeen, HA Alhazmi… - Molecules, 2020 - mdpi.com
Viral infections and associated diseases are responsible for a substantial number of
mortality and public health problems around the world. Each year, infectious diseases kill …

[HTML][HTML] Chemical diversity and activity profiles of HIV-1 reverse transcriptase inhibitors from plants

KC Chinsembu - Revista Brasileira de Farmacognosia, 2019 - Elsevier
Current challenges to antiretroviral therapy have opened new vistas in the search for novel
drugs from natural products. This review focusses on plants as sources of inhibitors for …

Traveling Wave Ion Mobility-Derived Collision Cross Section Database for Plant Specialized Metabolites: An Application to Ventilago harmandiana Pierre

N Jariyasopit, S Limjiasahapong… - Journal of Proteome …, 2022 - ACS Publications
The combination of ion mobility mass spectrometry (IM-MS) and chromatography is a
valuable tool for identifying compounds in natural products. In this study, using an ultra …

Naturally Occurring Xanthones; Biological Activities, Chemical Profiles and In Silico Drug Discovery

HR El-Seedi, HMS Ibrahim, N Yosri… - Current Medicinal …, 2024 - benthamdirect.com
Xanthones are widely distributed polyphenols, present commonly in higher plants; Garcinia,
Calophyllum, Hypericum, Platonia, Mangifera, Gentiana and Swertia. Xanthone tricyclic …

Garcinoxanthones SV, new xanthone derivatives from the pericarps of Garcinia mangostana together with their cytotoxic and antioxidant activities

TH Tran, HT Le, HM Nguyen, TH Tran, T Do Thi… - Fitoterapia, 2021 - Elsevier
Abstract Xanthones (9H-xanthene-9-ones) are considered to be very promising compounds
due to a variety of interesting biological and pharmacological activities. In this study, column …

A comprehensive overview on the role of phytocompounds in human immunodeficiency virus treatment

CP Mandhata, CR Sahoo, RN Padhy - Journal of Integrative Medicine, 2023 - Elsevier
Acquired immune deficiency syndrome (AIDS) is a worldwide epidemic caused by human
immunodeficiency virus (HIV) infection. Newer medicines for eliminating the viral reservoir …

Naturally occurring simple oxygenated benzophenones: Structural diversity, distribution, and biological properties

T Marinov, Z Kokanova-Nedialkova, PT Nedialkov - Diversity, 2023 - mdpi.com
Naturally occurring benzophenones represent a relatively small group of plant metabolites
with narrow distribution, mainly in members of Clusiaceae, Gentianaceae, Hypericaceae …

Xanthones and biphenyls from the stems of Garcinia cylindrocarpa and their cytotoxicity

ER Sukandar, S Kaennakam, K Rassamee, P Siripong… - Fitoterapia, 2018 - Elsevier
Six new compounds including four new xanthones, cylindroxanthones D–G (1–4), and two
new biphenyls, cylindrobiphenyls A and B (5 and 6), were isolated from the stems of …

Bioactive xanthones, benzophenones and biphenyls from mangosteen root with potential anti-migration against hepatocellular carcinoma cells

S Choodej, K Koopklang, A Raksat, N Chuaypen… - Scientific Reports, 2022 - nature.com
Liver cancer refers primarily to hepatocellular carcinoma (HCC) accounting for over 90% of
cases and is the highest incidence in men in Thailand. Over the past decades, the incidence …