The melatonin receptor 1B gene links circadian rhythms and type 2 diabetes mellitus: An evolutionary story
H Zhu, Z Zhao, H Liu, J Cai, Q Lu, L Ji, J Xu - Annals of Medicine, 2023 - Taylor & Francis
Disturbed circadian rhythms have been a risk factor for type 2 diabetes mellitus (T2DM).
Melatonin is the major chronobiotic hormone regulating both circadian rhythm and glucose …
Melatonin is the major chronobiotic hormone regulating both circadian rhythm and glucose …
Measuring sleep regularity: theoretical properties and practical usage of existing metrics
Abstract Study Objectives Sleep regularity predicts many health-related outcomes. Currently,
however, there is no systematic approach to measuring sleep regularity. Traditionally …
however, there is no systematic approach to measuring sleep regularity. Traditionally …
Towards the recognition of oligogenic forms of type 2 diabetes
L Le Collen, P Froguel, A Bonnefond - Trends in Endocrinology & …, 2024 - cell.com
The demarcation between monogenic and polygenic type 2 diabetes (T2D) is less distinct
than previously believed. Notably, recent research has highlighted a new entity, that we …
than previously believed. Notably, recent research has highlighted a new entity, that we …
Explanatory variables of objectively measured 24-h movement behaviors in people with prediabetes and type 2 diabetes: A systematic review
L Bogaert, I Willems, P Calders, E Dirinck… - Diabetes & Metabolic …, 2024 - Elsevier
Aim Physical activity (PA), sedentary behavior (SB) and sleep (ie 24-h movement behaviors)
are associated with health indicators in people with prediabetes and type 2 diabetes (T2D) …
are associated with health indicators in people with prediabetes and type 2 diabetes (T2D) …
AI-Driven sleep staging from actigraphy and heart rate
TA Song, SR Chowdhury, M Malekzadeh, S Harrison… - Plos one, 2023 - journals.plos.org
Sleep is an important indicator of a person's health, and its accurate and cost-effective
quantification is of great value in healthcare. The gold standard for sleep assessment and …
quantification is of great value in healthcare. The gold standard for sleep assessment and …
A lower sleep regularity index (SRI) is associated with relapse in individuals with alcohol use disorder following inpatient treatment
The sleep regularity index (SRI) is used to measure an individual's sleep/wake consistency
over time. The SRI has been associated with certain health risks; to date, research …
over time. The SRI has been associated with certain health risks; to date, research …
[HTML][HTML] Interaction of night shift work with polymorphism in melatonin receptor 1B gene on incident stroke
Objectives The aim of this study was to investigate whether melatonin receptor type 1B
(MTNR1B) rs10830963 polymorphism interacts with night shift work on the risk of incident …
(MTNR1B) rs10830963 polymorphism interacts with night shift work on the risk of incident …
Molecular basis of ligand selectivity for melatonin receptors
Sleep disorders in adults are related to adverse health effects such as reduced quality of life
and increased mortality. About 30–40% of adults are suffering from different sleep disorders …
and increased mortality. About 30–40% of adults are suffering from different sleep disorders …
Effect and mechanism of exogenous melatonin on cognitive deficits in animal models of Alzheimer's disease: a systematic review and meta-analysis
Z Zhai, D Xie, T Qin, Y Zhong, Y Xu, T Sun - Neuroscience, 2022 - Elsevier
Melatonin (MT) has been reported to control and prevent Alzheimer's disease (AD) in the
clinic; however, the effect and mechanism of MT on AD have not been specifically described …
clinic; however, the effect and mechanism of MT on AD have not been specifically described …
Identification of key regions mediating human melatonin type 1 receptor functional selectivity revealed by natural variants
A Hegron, E Huh, X Deupi, B Sokrat… - ACS Pharmacology & …, 2021 - ACS Publications
Melatonin is a hormone mainly produced by the pineal gland and MT1 is one of the two G
protein-coupled receptors (GPCRs) mediating its action. Despite an increasing number of …
protein-coupled receptors (GPCRs) mediating its action. Despite an increasing number of …