Myocardial infarction (MI) is a leading cause of morbidity and mortality worldwide. As
mitochondrial dysfunction critically contributes to the pathogenesis of MI, intensive research …

Naturally occurring compounds polyphenols are secondary metabolites of plants, comprised
several categories, namely, flavonoids, phenolic acids, lignans and stilbenes. The biological …

Aging is a fundamental biological process accompanied by a general decline in tissue
function. Indeed, as the lifespan increases, age-related dysfunction, such as cognitive …

Mitochondrial remodeling is dysregulated in metabolic diseases but the underlying
mechanism is not fully understood. We report here that BDNF (brain derived neurotrophic …

Defective mitophagy is causally linked to obesity complications. Here, we identified an
interaction between mitophagy protein FUNDC1 (FUN14 domain containing 1) and receptor …

Mitophagy serves as a cardinal regulator in the maintenance of mitochondrial integrity,
function, and cardiovascular homeostasis, through the fine control and governance of …

Mitochondria and mitochondria‐mediated signalling pathways are known to control synaptic
signalling, as well as long‐lasting changes in neuronal structure and function. Mitochondrial …

Mitochondrial dysfunction may play a crucial role in various diseases due to its roles in the
regulation of energy production and cellular metabolism. Serine/threonine kinase (AKT) is a …

Simple Summary The roles of peroxisome proliferator-activated receptors (PPARs) in
carcinogenesis are increasingly appreciated. With the growing interest in tumor stromal …

Fibrosis occurs in most human organs including the liver, lung, heart and kidney, and is
crucial for the progression of most chronic diseases. As an indispensable catabolic process …