Endometrial cancer (EC) is a gynecological pathology that affects the uterine inner lining. In
recent years, genomic studies revealed continually evolving mutational landscapes of …

Androgens play an essential role in prostate cancer. Clinical treatments that target
steroidogenesis and the androgen receptor (AR) successfully postpone disease …

As the major component of cell membranes, phosphatidylcholine (PC) is synthesized de
novo in the Kennedy pathway and then undergoes extensive deacylation-reacylation …

The formyl peptide receptor 1 (FPR1) is primarily responsible for detection of short peptides
bearing N-formylated methionine (fMet) that are characteristic of protein synthesis in bacteria …

Strategies for patient stratification and early intervention are required to improve clinical
benefits for patients with prostate cancer. Here, we found that active DHEA utilization in the …

Background Hepatocellular carcinoma (HCC) remains one of the most common malignant
neoplasms. Lysophosphatidylcholine acyltransferase 1 (LPCAT1) plays a key role in the …

Prostate cancer continuously progresses following deprivation of circulating androgens
originating from the testis and adrenal glands, indicating the existence of oncometabolites …

Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is the second-deadliest
infectious disease worldwide. Emerging evidence shows that the elongation factor EF-Tu …

Dolichol is a lipid critical for N-glycosylation as a carrier for activated sugars and nascent
oligosaccharides. It is commonly thought to be directly produced from polyprenol by the …

Simple Summary Dihydrotestosterone (DHT), the most potent androgen hormone, is an
important aetiologic factor of androgenetic alopecia (AGA), or hair loss. Steroid 5-alpha …