Ocular ischemic syndrome (OIS) is one of the severe ocular disorders occurring from
stenosis or occlusion of the carotid arteries. As the ophthalmic artery is derived from the …

The cerebellum is crucial for both motor and nonmotor functions. Alzheimer's disease (AD),
alongside other dementias such as vascular dementia (VaD), Lewy body dementia (DLB) …

Pterostilbene, a methylated stilbene derived from many plant foods, has significant anti-
inflammatory activity. Meanwhile, vascular dementia (VaD) is the second most common …

Methods The rat model with vascular cognitive impairment was established by permanent
bilateral common carotid artery occlusion (BCCAO). The observing time-points were …

Chronic cerebral hypoperfusion during aging may cause progressive neurodegeneration as
ischemic conditions persist. Proper functioning of the interplay between neurons and glia is …

Chronic cerebral hypoperfusion (CCH) is a cardinal risk factor for Parkinson's disease
dementia (PDD), but this potential causality lacks mechanistic evidence. We selected …

Background and purpose The cAMP response element binding protein (CREB) plays an
important role in the mechanism of cognitive impairment and is also pivotal in the switch …

Cerebral hypoperfusion induced by bilateral common carotid artery occlusion (BCCAo) in
rodents has been proposed as an experimental model of white matter damage and vascular …

The present study aimed to determine the effect of 3', 4'-dihydroxyflavonol (DiOHF) on
apoptosis in the cerebellum and hippocampus in rats with ischemia-reperfusion. A total of 38 …

In addition to roles in motor coordination, the cerebellum is also associated with cognitive
function. The aim of the present study was to investigate the effect of treadmill exercise on …