Platelet–leucocyte aggregates as novel biomarkers in cardiovascular diseases

K Pluta, K Porębska, T Urbanowicz, A Gąsecka… - Biology, 2022 - mdpi.com
Simple Summary Cardiovascular diseases are the most common cause of death worldwide.
Hence, novel biomarkers are urgently needed to improve diagnosis and treatment. Platelet …

Biologicals, platelet apoptosis and human diseases: an outlook

RM Thushara, M Hemshekhar, K Kemparaju… - Critical reviews in …, 2015 - Elsevier
Platelets, once considered mediators of hemostasis and thrombosis, are now known to be
involved in wound healing, inflammation, cardiovascular diseases, diabetes, arthritis, and …

Rutin and curcumin reduce inflammation, triglyceride levels and ADA activity in serum and immune cells in a model of hyperlipidemia

AG Manzoni, DF Passos, JLG da Silva… - Blood Cells, Molecules …, 2019 - Elsevier
Hyperlipidemia is associated with endothelial dysfunction and inflammatory disorders.
Adenosine and adenosine deaminase (ADA) modulate immune responses and lipid …

Protocatechuic acid protects platelets from apoptosis via inhibiting oxidative stress-mediated PI3K/Akt/GSK3β signaling

F Ya, K Li, H Chen, Z Tian, Y Shi, F Song… - Thrombosis and …, 2021 - thieme-connect.com
Oxidative stress plays crucial roles in initiating platelet apoptosis that facilitates the
progression of cardiovascular diseases (CVDs). Protocatechuic acid (PCA), a major …

Effects of Danhong injection on platelet aggregation in hyperlipidemia rats

H Fan, M Li, L Yu, W Jin, J Yang, Y Zhang… - Journal of …, 2018 - Elsevier
Abstract Ethnopharmacological relevance Danhong Injection (DHI), a Chinese medical
product extracted from Radix et Rhizoma Salviae Miltiorrhizae (Salvia miltiorrhiza Bge …

Effects of astaxanthin on blood coagulation, fibrinolysis and platelet aggregation in hyperlipidemic rats

ZY Deng, WG Shan, SF Wang, MM Hu… - Pharmaceutical …, 2017 - Taylor & Francis
Context: Astaxanthin (ASTX) is a xanthophyll carotenoid that reduces hemostasis in
hyperlipidemic organisms. Its antihemostatic mechanisms remain unclear. Objective: The …

Pharmacological control of platelet-leukocyte interactions by the human anti-P-selectin antibody inclacumab–preclinical and clinical studies

D Kling, C Stucki, S Kronenberg, D Tuerck… - Thrombosis …, 2013 - Elsevier
BACKGROUND AND OBJECTIVE: Elevated levels of platelet-leukocyte aggregates (PLAs)
have been reported in several cardiovascular diseases and suggested to contribute to …

[PDF][PDF] Cinnamon inhibits platelet function and improves cardiovascular system

M Mehrpouri, R Hamidpour, M Hamidpour… - Journal of Medicinal …, 2020 - jmp.ir
Background: Cinnamon belongs to the Lauraceae family and is one of the most common
spices that are used as traditional medicine in the world. The bark and leaf of cinnamon …

[PDF][PDF] The impact of hyperglycemia and hyperlipidemia on plasma P-selectin and platelet markers after ischemic stroke

M Pawelczyk, B Kaczorowska, Z Baj - Archives of Medical Science, 2017 - termedia.pl
Results: We observed a significant influence of hyperlipidemia and hyperglycemia on sP-
selectin concentration. A strong correlation between higher sP-selectin concentration and …

Elevation of monocyte-platelet aggregates is an early marker of type 2 diabetes

Z Patkó, A Császár, G Acsády, I Őry… - … Medicine and Applied …, 2012 - akjournals.com
Background Diabetes has been shown to be an accelerating factor in the progression of
atherosclerosis. The metabolic changes in diabetes contribute to modified platelet function …