Selenium is an essential trace element that is involved in the synthesis of various
selenoproteins in higher animals including humans. Twenty five selenoproteins have been …

This Guidance document describes harmonised risk assessment methodologies for
combined exposure to multiple chemicals for all relevant areas within EFSA's remit, ie …

Although the need for non-animal alternatives has been well recognised for the human
health hazard assessment of chemicals in general, it has become especially pressing for …

Abstract The Scientific Committee confirms that the Threshold of Toxicological Concern
(TTC) is a pragmatic screening and prioritisation tool for use in food safety assessment. This …

The long-term investment in new approach methodologies (NAMs) within the EU and other
parts of the world is beginning to result in an emerging consensus of how to use information …

The Scientific Committee confirms that the Threshold of Toxicological Concern (TTC) is a
pragmatic screening and prioritisation tool for use in food safety assessment. This Guidance …

Toxicological risk assessment of contaminants of emerging concern (CEC) in (sources of)
drinking water is required to identify potential health risks and prioritize chemicals for …

Synthetic and naturally occurring substances present in food and feed, together with their
possible breakdown or reaction products, represent a large number of substances, many of …

A new dataset of cosmetics-related chemicals for the Threshold of Toxicological Concern
(TTC) approach has been compiled, comprising 552 chemicals with 219, 40, and 293 …

In light of the increasing interest in development of sustainable potable reuse systems,
additional research is needed to elucidate the risks of producing drinking water from new …