Increasing evidence from animal and epidemiological studies indicates that perinatal
exposure to pesticides cause developmental neurotoxicity and may increase the risk for …

The prevailing dogma is that chlorpyrifos (CPF) mediates its toxicity through inhibition of
cholinesterase (ChE). However, in recent years, the toxicological effects of developmental …

Antidepressant drugs are usually administered for several weeks for the treatment of major
depressive disorder. However, they are also prescribed in several additional psychiatric …

In Chile, agriculture is a relevant economic activity and is concomitant with the use of
pesticides to improve the yields. Acute intoxications of agricultural workers occur with some …

Autoantibodies from autistic spectrum disorder (ASD) patients react with multiple proteins
expressed in the brain. One such autoantibody targets myelin basic protein (MBP). ASD …

Chlorpyrifos (CPF) is an organophosphate (OP) insecticide that is metabolically activated to
the highly toxic chlorpyrifos oxon. Dietary exposure is the main route of intoxication for non …

Organophosphates (OPs) affect behavior by inhibiting acetylcholinesterase (AChE). While
the cognitive short-term effects may be directly attributed to this inhibition, the mechanisms …

Background Health effects of pesticides are easily diagnosed when acute poisonings
occurs, nevertheless, consequences from chronic exposure can only be observed when …

Protein structure and dynamics are crucial for protein function. Thus, the study of
conformational properties can be very informative for characterizing new proteins and to …

Organophosphates (OPs) are important toxic compounds commonly used for a variety of
purposes in agriculture, industry and household settings. It has been well established that …