People with damage to the orbitofrontal cortex (OFC) have specific problems making
decisions, whereas their other cognitive functions are spared. Neurophysiological studies …

Economic choice behavior entails the computation and comparison of subjective values. A
central contribution of neuroeconomics has been to show that subjective values are …

The prefrontal cortex makes up almost a quarter of the human brain, and it expanded
dramatically during primate evolution. The Neurobiology of the Prefrontal Cortex presents a …

Traditionally the object of economic theory and experimental psychology, economic choice
recently became a lively research focus in systems neuroscience. Here I summarize the …

Two ideas have dominated neuropsychology concerning the orbitofrontal cortex (OFC). One
holds that OFC regulates emotion and enhances behavioral flexibility through inhibitory …

Recent evidence from monkey models of cognition shows that the magnocellular
subdivision of the mediodorsal thalamus (MDmc) is more critical for learning new …

The estimated values of choices, and therefore decision-making based on those values, are
influenced by both the chance that the chosen items or goods can be obtained (availability) …

Dense amnesia can result from damage to the medial diencephalon in humans and in
animals. In humans this damage is diffuse and can include the mediodorsal nuclei of the …

Advantageous foraging choices benefit from an estimation of two aspects of a resource's
value: its current desirability and availability. Both orbitofrontal and ventrolateral prefrontal …

While making economic choices, individuals assign subjective values to the available
options. Values computed in different behavioral conditions, however, can vary substantially …