A cornerstone of statistical inference, the maximum entropy framework is being increasingly
applied to construct descriptive and predictive models of biological systems, especially …

Which properties of metabolic networks can be derived solely from stoichiometry? Predictive
results have been obtained by flux balance analysis (FBA), by postulating that cells set …

The uniform sampling of convex polytopes is an interesting computational problem with
many applications in inference from linear constraints, but the performances of sampling …

Assuming a steady-state condition within a cell, metabolic fluxes satisfy an underdetermined
linear system of stoichiometric equations. Characterizing the space of fluxes that satisfy such …

In a complex system, perturbations propagate by following paths on the network of
interactions among the system's units. In contrast to what happens with the spreading of …

In multiple scientific and technological applications we face the problem of having low
dimensional data to be justified by a linear model defined in a high dimensional parameter …

Motivation Genome-scale metabolic networks can be modeled in a constraint-based
fashion. Reaction stoichiometry combined with flux capacity constraints determine the space …

We show that a steady-state stock-flow consistent macro-economic model can be
represented as a Constraint Satisfaction Problem (CSP). The set of solutions is a polytope …

Experimental and empirical observations on cell metabolism cannot be understood as a
whole without their integration into a consistent systematic framework. However, the …

Возможность получать большие массивы разнородных данных о компонентах
животной клетки с помощью высокопроизводительных молекулярно-биологических …