Spectrofluorimetric quantitative analysis of favipiravir, remdesivir and hydroxychloroquine in spiked human plasma

S Ramzy, AH Abdelazim, AOE Osman… - Spectrochimica Acta Part …, 2022 - Elsevier
Favipiravir, remdesivir and hydroxychloroquine have been suggested in COVID-19
Treatment Guidelines Panel of many countries. Synchronous spectrofluorometric …

An innovative polymer-based electrochemical sensor encrusted with Tb nanoparticles for the detection of favipiravir: a potential antiviral drug for the treatment of …

MFB Ali, RE Saraya, S El Deeb, AE Ibrahim, BI Salman - Biosensors, 2023 - mdpi.com
An innovative polymer-based electro-sensor decorated with Tb nanoparticles has been
developed for the first time. The fabricated sensor was utilized for trace determination of …

A solvent-free HPLC method for the simultaneous determination of Favipiravir and its hydrolytic degradation product

YA Sharaf, MH Abd El-Fattah, HM El-Sayed… - Scientific Reports, 2023 - nature.com
Abstract During COVID-19 pandemic, Favipiravir (FPV) showed a great efficacy against
COVID-19 virus, it produced noticeable improvements in recovery of the patients. The aim of …

Quantitative analysis of two COVID-19 antiviral agents, favipiravir and remdesivir, in spiked human plasma using spectrophotometric methods; greenness evaluation

AS Batubara, AH Abdelazim, AA Almrasy, M Gamal… - BMC chemistry, 2023 - Springer
Favipiravir and remdesivir have been included in the COVID-19 treatment guidelines panel
of several countries. The main objective of the current work is to develop the first validated …

Illuminating the analytical chemistry Profile: A Three-Decade comprehensive review of fluorometric quantitation in pharmaceutical formulations

R Kotadiya - Microchemical Journal, 2024 - Elsevier
Owing to its high sensitivity and specificity, fluorescence spectroscopy has emerged as a
critical analytical tool for pharmaceutical formulations. Over the last three decades, it has …

Highly selective and sensitive potentiometric determination of favipiravir in COVID-19 antiviral drug formulations

C Topcu, S Aydin, BH Atasoy, RR Yilmaz, F Coldur… - Microchemical …, 2024 - Elsevier
In this study, a novel all-solid-state electrochemical sensor based on favipiravir-
tetraphenylborate (FAV-TPB) electroactive material was developed and reported for FAV's …

Analytical performance and greenness evaluation of five multi-level design models utilized for impurity profiling of favipiravir, a promising COVID-19 antiviral drug

AE Ibrahim, YA Sharaf, S El Deeb, RA Sayed - Molecules, 2022 - mdpi.com
In 2018, the discovery of carcinogenic nitrosamine process related impurities (PRIs) in a
group of widely used drugs led to the recall and complete withdrawal of several medications …

Micellar-enhanced and green-assessed first-derivative synchronous spectrofluorimetric approach for concurrent determination of alfuzosin hydrochloride and …

RA Sayed, AR Mohamed, A Shalaby… - Spectrochimica Acta Part A …, 2023 - Elsevier
Alfuzosin hydrochloride (AZH) is co-formulated with solifenacin succinate (SOS) in Solitral®
capsules for treating prostate hyperplasia in patients with overactive bladder syndrome …

Synchronous spectrofluorimetric determination of favipiravir and aspirin at the nano-gram scale in spiked human plasma; greenness evaluation

AS Batubara, BE Ainousah, S Ramzy… - … Acta Part A: Molecular …, 2023 - Elsevier
Favipiravir and aspirin are co-administered during COVID-19 treatment to prevent venous
thromboembolism. For the first time, a spectrofluorometric method has been developed for …

Spectrophotometric determination of favipiravir in presence of its acid hydrolysis product

YA Sharaf, MH Abd El-Fattah, HM El-Sayed… - BMC chemistry, 2023 - Springer
Favipiravir (FAV) has been approved as an antiviral drug used in pandemic corona virus to
treat covid-19. It has an amide moiety susceptible to hydrolysis and degradation in acid …