Metabolism and ATP levels within the oocyte and adjacent cumulus cells are associated
with quality of oocyte and optimal development of a healthy embryo. Lipid metabolism …

Mammalian oocytes and early cleavage-stage embryos are critically dependent on their~
100,000 mitochondria to develop from ovulation to compacted morula stage. They rely …

Obesity, diabetes, and related metabolic disorders are major health issues worldwide. As
the epidemic of metabolic disorders continues, the associated medical co-morbidities …

Lipid droplets (LDs) in steroidogenic tissues have a cholesteryl ester (CE) core surrounded
by a phospholipid monolayer that is coated with associated proteins. Compared with other …

OBJECTIVE: To determine whether the high lipid content of human follicular fluid influences
oocyte maturation. DESIGN: Mouse oocytes as substitutes for human oocytes were exposed …

The ability of an oocyte to undergo successful cytoplasmic and nuclear maturation,
fertilization and embryo development is referred to as the oocyte's quality or developmental …

Obesity in women is a concern in many countries. This causes numerous health issues;
however, this review focuses on the impact of obesity on women's reproduction, and in …

Oocyte maturation is a complex and dynamic process regulated by the coordination of
ovarian cells and numerous extraovarian signals. From mammal studies, it is learnt that lipid …

Successful embryo and fetal development is dependent on the quality of the oocyte from
which it was derived. Several studies to date have demonstrated the link between …

Mobilization of fatty acids from adipose tissue during metabolic stress increases the amount
of free fatty acids in blood and follicular fluid and is associated with impaired female fertility …