Treatment of locally advanced rectal cancer in the era of total neoadjuvant therapy: a systematic review and network meta-analysis

G Turri, G Ostuzzi, G Vita, V Barresi, A Scarpa… - JAMA Network …, 2024 - jamanetwork.com
Importance Treatment of locally advanced rectal cancer (LARC) involves neoadjuvant
chemoradiotherapy plus total mesorectal excision and adjuvant chemotherapy. However …

Treatment response prediction using MRI‐based pre‐, post‐, and delta‐radiomic features and machine learning algorithms in colorectal cancer

S Shayesteh, M Nazari, A Salahshour… - Medical …, 2021 - Wiley Online Library
Objectives We evaluate the feasibility of treatment response prediction using MRI‐based pre‐
, post‐, and delta‐radiomic features for locally advanced rectal cancer (LARC) patients …

Addition of platinum derivatives to fluoropyrimidine-based neoadjuvant chemoradiotherapy for stage II/III rectal cancer: systematic review and meta-analysis

FJ Hüttner, P Probst, E Kalkum… - JNCI: Journal of the …, 2019 - academic.oup.com
Background Current guidelines recommend neoadjuvant therapy for patients with stage II or
III rectal cancer. The addition of platinum derivatives to fluoropyrimidine-based …

Complete pathological response in rectal cancer utilising novel treatment strategies for neo-adjuvant therapy: A systematic review

K Wilson, M Flood, V Narasimhan, T Pham… - European Journal of …, 2021 - Elsevier
Background Locally advanced rectal cancer is routinely treated with neo-adjuvant long
course chemoradiotherapy or short course radiotherapy, followed by total mesorectal …

Neo-adjuvant chemoradiotherapy response prediction using MRI based ensemble learning method in rectal cancer patients

SP Shayesteh, A Alikhassi, AF Esfahani, M Miraie… - Physica Medica, 2019 - Elsevier
Objectives The aim of this study was to investigate and validate the performance of
individual and ensemble machine learning models (EMLMs) based on magnetic resonance …

Prediction of response to neoadjuvant chemoradiotherapy by MRI-based machine learning texture analysis in rectal cancer patients

SP Shayesteh, A Alikhassi, F Farhan… - Journal of …, 2020 - Springer
Introduction Neoadjuvant chemoradiotherapy (nCRT) followed by surgical resection is the
standard treatment for locally advanced rectal cancer (LARC). Radiomics can be used as …

Role of Oxaliplatin in the Neoadjuvant Concurrent Chemoradiotherapy in Locally Advanced Rectal Cancer: a Review of Evidence

R Nazari, GN Piozzi, R Ghalehtaki… - Clinical Medicine …, 2024 - journals.sagepub.com
The treatment of locally advanced rectal cancer (LARC) is a challenging situation for
radiation oncologists and colorectal surgeons. Most current approaches recommend …

Early MRI predictors of disease-free survival in locally advanced rectal cancer from the GRECCAR 4 trial

S Nougaret, F Castan, H Forges… - Journal of British …, 2019 - academic.oup.com
Background Tailored neoadjuvant treatment of locally advanced rectal cancer (LARC) may
improve outcomes. The aim of this study was to determine early MRI prognostic parameters …

Phase II randomized trial of capecitabine with bevacizumab and external beam radiation therapy as preoperative treatment for patients with resectable locally …

R Salazar, J Capdevila, JL Manzano, C Pericay… - BMC cancer, 2020 - Springer
Background Preoperative chemoradiotherapy with capecitabine is considered as a standard
of care for locally advanced rectal cancer. The “Tratamiento de Tumores Digestivos” group …

[HTML][HTML] Preoperative short course radiotherapy with concurrent and consolidation chemotherapies followed by delayed surgery in locally advanced rectal cancer …

M Aghili, S Sotoudeh, R Ghalehtaki… - Radiation Oncology …, 2018 - ncbi.nlm.nih.gov
Purpose This study aimed to assess complications and outcomes of a new approach, that is,
combining short course radiotherapy (SRT), concurrent and consolidative chemotherapies …