The aim of this review is to focus on the molecular factors that ensure the optimal
development and maintenance of the mammary gland thanks to their integration and …

OTX homeobox genes have been extensively studied for their role in development,
especially in neuroectoderm formation. Recently, their expression has also been reported in …

BACKGROUND Adenoid cystic carcinoma (ACC), 1 of the most common salivary gland
malignancies, arises from the intercalated ducts, which are composed of inner ductal …

Orthodenticle homeobox (OTX1) is reported to be involved in numerous cancers, but the
expression level and molecular function of OTX1 in gallbladder cancer (GBC) remain …

Orthodenticlehomeobox 1 (OTX1) overexpression had previously been associated with the
progression of several tumors. The present study aimed to determine the expression and …

Abstract Orthodenticle homolog 1 (OTX1) has previously been revealed to be tightly
associated with the development and progression of several human tumors. However, the …

Bladder cancer (BC) is one of the most aggressive tumors worldwide. OTX1 (orthodenticle
homeobox 1) is an important transcription factor involved in various diseases, such as …

Abstract Background Orthodenticle homeobox 1 (OTX1) is a transcription factor that plays an
important role in various human cancers. However, the function of OTX1 in laryngeal …

Background Endocrine therapy is highly effective in blocking the estrogen receptor pathway
in HR+/HER2–early breast cancer (EBC). However, up to 40% of patients experience …

The most prevalent kind of primary brain tumors, gliomas, have a dismal prognosis. Recent
advances in the tumor-promoting ability of OTX1 have drawn increasing attention. The …