Aquaporin 4: a player in cerebral edema and neuroinflammation
Neuroinflammation is a common pathological event observed in many different brain
diseases, frequently associated with blood brain barrier (BBB) dysfunction and followed by …
diseases, frequently associated with blood brain barrier (BBB) dysfunction and followed by …
Aquaporin and brain diseases
Background The presence of water channel proteins, aquaporins (AQPs), in the brain led to
intense research in understanding the underlying roles of each of them under normal …
intense research in understanding the underlying roles of each of them under normal …
Intranasal administration of oxytocin: behavioral and clinical effects, a review
JG Veening, B Olivier - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
The intranasal (IN-) administration of substances is attracting attention from scientists as well
as pharmaceutical companies. The effects are surprisingly fast and specific. The present …
as pharmaceutical companies. The effects are surprisingly fast and specific. The present …
Posttraumatic reduction of edema with aquaporin-4 RNA interference improves acute and chronic functional recovery
Traumatic brain injury (TBI) is common in young children and adolescents and is associated
with long-term disability and mortality. The neuropathologic sequelae that result from …
with long-term disability and mortality. The neuropathologic sequelae that result from …
Connexin 43: an interface connecting neuroinflammation to depression
H Jiang, Y Zhang, ZZ Wang, NH Chen - Molecules, 2023 - mdpi.com
Major depressive disorder (MDD) is a leading chronic mental illness worldwide,
characterized by anhedonia, pessimism and even suicidal thoughts. Connexin 43 (Cx43) …
characterized by anhedonia, pessimism and even suicidal thoughts. Connexin 43 (Cx43) …
In vitro modeling of the blood–brain barrier for the study of physiological conditions and Alzheimer's disease
The blood–brain barrier (BBB) is an essential structure for the maintenance of brain
homeostasis. Alterations to the BBB are linked with a myriad of pathological conditions and …
homeostasis. Alterations to the BBB are linked with a myriad of pathological conditions and …
Assessment of HBEC-5i endothelial cell line cultivated in astrocyte conditioned medium as a human blood-brain barrier model for ABC drug transport studies
Endothelial cells are main components of the Blood-Brain Barrier (BBB) and form a tight
monolayer that regulates the passage of molecules, with the ATP-Binding Cassette (ABC) …
monolayer that regulates the passage of molecules, with the ATP-Binding Cassette (ABC) …
The pivotal role of astrocytes in an in vitro stroke model of the blood-brain barrier
W Neuhaus, F Gaiser, A Mahringer, J Franz… - Frontiers in cellular …, 2014 - frontiersin.org
Stabilization of the blood-brain barrier during and after stroke can lead to less adverse
outcome. For elucidation of underlying mechanisms and development of novel therapeutic …
outcome. For elucidation of underlying mechanisms and development of novel therapeutic …
Reduced graphene oxide induces transient blood–brain barrier opening: an in vivo study
MCP Mendonça, ES Soares, MB de Jesus… - Journal of …, 2015 - Springer
Background The blood–brain barrier (BBB) is a complex physical and functional barrier
protecting the central nervous system from physical and chemical insults. Nevertheless, it …
protecting the central nervous system from physical and chemical insults. Nevertheless, it …
Comparison of PPAR ligands as modulators of resolution of inflammation, via their influence on cytokines and oxylipins release in astrocytes
DV Chistyakov, AA Astakhova, SV Goriainov… - International journal of …, 2020 - mdpi.com
Neuroinflammation is a key process of many neurodegenerative diseases and other brain
disturbances, and astrocytes play an essential role in neuroinflammation. Therefore, the …
disturbances, and astrocytes play an essential role in neuroinflammation. Therefore, the …