The novel object recognition test (NOR) test is a two trial cognitive paradigm that assesses
recognition memory. Recognition memory is disturbed in a range of human disorders and …

The administration of reserpine to rodents was one of the first models used to investigate the
pathophysiology and screening for potential treatments of P arkinson's disease (PD). The …

Animal models are widely used to study alterations caused by Parkinson's disease (PD).
However, in general, pharmacological models do not express the progressive nature of the …

Background Concerns over the neurotoxic potential of retained gadolinium in brain tissues
after intravenous gadolinium-based contrast agent (GBCA) administration have led to …

Depression remains a significant public health concern, and current animal models of
depression are limited in their ability to accurately mimic human depression. However …

Studies have suggested that cognitive deficits can precede motor alterations in Parkinson's
disease (PD). However, in general, classic animal models are based on severe motor …

Animal models are widely used to study antidepressant-like effect in rodents. However, it
should be mentioned that pharmacological models do not always take into account the …

Rasagiline mesylate is used as first line agent for early management of Parkinson's disease
but its water soluble nature creates hurdles to cross blood brain barrier also its low oral …

Cannabidiol (CBD) is a non-psychotomimetic compound from Cannabis sativa that presents
antipsychotic, anxiolytic, anti-inflammatory, and neuroprotective effects. In Parkinson's …

Parkinson's disease (PD) is a widespread neurodegenerative disorder occurs due to the
degradation of dopaminergic neurons present in the substantia nigra pars compacta (SNpc) …