Substance use disorder (SUD) is a chronic, relapsing disease with a highly multifaceted
pathology that includes (but is not limited to) sensitivity to drug-associated cues, negative …

Cannabis is the most commonly used illicit drug worldwide, with~ 5 million daily users
worldwide. Emerging evidence supports a number of associations between cannabis and …

Drug addiction presents as a chronic relapsing disorder characterized by persistent drug‐
seeking and drug‐taking behaviours. Given the significant detrimental effects of this disease …

Recent insights have demonstrated a central role for dopaminergic neurotransmission in
modulating pain perception and natural analgesia within supraspinal regions, including the …

The influence of cannabis on mental health receives growing scientific and political
attention. An increasing demand for treatment of cannabis dependence has refueled the …

The association between cannabis use and psychosis has long been recognized. Recent
advances in knowledge about cannabinoid receptor function have renewed interest in this …

Rationale Elevated dopamine function is thought to play a key role in both the rewarding
effects of addictive drugs and the pathophysiology of schizophrenia. Accumulating …

Abstract Purpose of the Review Cannabis is the most commonly used illicit substance
worldwide. In recent decades, highly concentrated products have flooded the market, and …

Addiction research has historically neglected research on women, and most studies have
been conducted on men only, with the concluding results generalized to the female …

Despite the high prevalence of marijuana use among pregnant women and adolescents, the
impact of cannabis on the developing brain is still not well understood. However, growing …