Ion concentration polarization focusing (ICPF) is an electrokinetic technique, in which
analytes are enriched and separated along a localized electric field gradient in the presence …

Enzymes have essential roles in catalyzing biological reactions and maintaining metabolic
systems. Many in vitro enzymatic bioassays have been developed for use in industrial and …

Microfluidic paper-based analytical devices (μPADs) have attracted significant attention in
the field of point-of-care (POC) diagnostics. However, the heterogeneous structure of the …

In this work, we investigated three single straight microchannel designs for the microfluidic
biomolecule concentration device, including one traditional single channel and two …

Separation and isolation of suspended submicron particles is fundamental to a wide range
of applications, including desalination, chemical processing, and medical diagnostics. Ion …

Preconcentration of biomolecules based on ion concentration polarization (ICP) has been
splendidly applied to various biomedical and chemical processes. However, in many …

A convergent sector in microfluidic devices utilizing ion concentration polarization (ICP) can
help increase the preconcentration rate and the concentration enhancement factor (CEF) of …

Over the past few years, the detection of biological analytes has intensively been studied to
understand the biodiagnostics of various diseases [1]. Some of the analytes that have been …

One of the most cited limitations of biochemical detection is its poor sensitivity, owing to the
relatively high complexity of micro‐samples. Moreover, some samples cannot be easily self …

Low concentration of biomarkers (proteins, nucleic acids, metabolites) is a major concern in
early disease diagnosis due to the very low concentration of these biomarkers at the early …