Pesticide exposure and risk of Alzheimer's disease: a systematic review and meta-analysis

D Yan, Y Zhang, L Liu, H Yan - Scientific reports, 2016 - nature.com
Evidence suggests that lifelong cumulative exposure to pesticides may generate lasting
toxic effects on the central nervous system and contribute to the development of Alzheimer's …

The association between toxic pesticide environmental exposure and Alzheimer's disease: A scientometric and visualization analysis

Y Li, R Fang, Z Liu, L Jiang, J Zhang, H Li, C Liu, F Li - Chemosphere, 2021 - Elsevier
Alzheimer's disease (AD) is one of the most common neurodegenerative diseases. The
association between environmental factors (eg, pesticide) and AD has attracted …

Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment

D Mattei, A Ivanov, C Ferrai, P Jordan… - Translational …, 2017 - nature.com
Maternal immune activation (MIA) during pregnancy has been linked to an increased risk of
developing psychiatric pathologies in later life. This link may be bridged by a defective …

Epigenetics of dementia: understanding the disease as a transformation rather than a state

B Maloney, DK Lahiri - The Lancet Neurology, 2016 - thelancet.com
Alzheimer's disease and other idiopathic dementias are associated with epigenetic
transformations. These transformations connect the environment and genes to …

Interdisciplinary fetal-neonatal neurology training applies neural exposome perspectives to neurology principles and practice

MS Scher - Frontiers in neurology, 2024 - frontiersin.org
An interdisciplinary fetal-neonatal neurology (FNN) program over the first 1,000 days
teaches perspectives of the neural exposome that are applicable across the life span. This …

Epigenetics and neurodegeneration: role of early-life nutrition

R Gabbianelli, E Damiani - The Journal of nutritional biochemistry, 2018 - Elsevier
Neurodegeneration represents a global problem due to the progressive increase in the
aging population all over the world. The quality of life in aging and the cost for the health …

An inter-disciplinary approach to evaluate human health risks due to long-term exposure to contaminated groundwater near a chemical complex

MMS Cabral Pinto, CM Ordens… - Exposure and …, 2020 - Springer
Potentially toxic elements (PTEs) are known to threat human health due to exposure to
contaminated groundwater. Some of these PTEs can lead to long-term carcinogenic and …

Heavy Metals of Santiago Island (Cape Verde) alluvial deposits: Baseline value maps and human health risk assessment

MMS Cabral Pinto, EA Ferreira da Silva - International journal of …, 2019 - mdpi.com
The chemical composition of surface geological materials may cause metabolic changes
and promote endemic diseases (eg, oncological, gastrointestinal, neurological or …

Human predisposition to cognitive impairment and its relation with environmental exposure to potentially toxic elements

MMS Cabral Pinto, AP Marinho-Reis, A Almeida… - … geochemistry and health, 2018 - Springer
New lines of evidence suggest that less than 10% of neurodegenerative diseases have a
strict genetic aetiology and other factors may be prevalent. Environmental exposures to …

Early life metal dysregulation in amyotrophic lateral sclerosis

C Figueroa‐Romero, KA Mikhail… - Annals of Clinical …, 2020 - Wiley Online Library
Objective Deficiencies and excess of essential elements and toxic metals are implicated in
amyotrophic lateral sclerosis (ALS), but the age when metal dysregulation appears remains …