Circadian rhythms and clock gene expressions are regulated by the suprachiasmatic
nucleus in the hypothalamus, and melatonin is produced in the pineal gland. Although the …

This review concerns the current knowledge of melatonin and alcohol-related disorders.
Chronobiological effects of ethanol are related to melatonin suppression and in relation to …

Excessive drinking of alcohol is becoming a worldwide problem, and people have
recognized that there exists a close relationship between chronic kidney disease (CKD) and …

Investigation of the pathogenesis of alcoholism in humans using different methodological
approaches has facilitated detection of important biological factors of consequent metabolic …

The aim of this study was to determine the effects of long-term administration of the oral
antidiabetic metformin or the pineal hormone melatonin, and a combination thereof, in …

Lipopolysaccharide (LPS) administration in an in vivo experimental mice model causes
oxidative damage in the liver, muscle, and kidney. We aimed to determine specific …

Chronic liver diseases are complications of thalassemia with iron overload. Iron chelators
are required to remove excessive iron, and antioxidants are supplemented to diminish …

The study establishes a link between alcoholism, inflammation state, and melatonin
synthesis. The aim of our study was to evaluate the effects of melatonin on changes in the …

1Department of Animal Nutrition and Biotechnology, and Fisheries, University of Agriculture
in Krakow, Al. Mickiewicza 24/28, 30-059 Kraków, Poland 2Department of Animal …

Melatonin (MLT), a natural compound found in the animal and vegetable kingdom,
participates in several physiological processes. MLT exerts antioxidant and anti …