Background Brain-derived neurotrophic factor (BDNF) is a neurotrophic factor expressed in
several tissues, including the brain, gut, and pancreas. Activation of the BDNF/TrkB/CREB …

Ischemic stroke is a leading cause of morbidity and mortality among type 2 diabetic patients.
Preclinical and translational studies have identified critical pathophysiological mediators of …

Rationale: A sedentary lifestyle is associated with increased risk for cardiovascular disease
(CVD). Smartwatches enable accurate daily activity monitoring for physical activity …

Background: Liver steatosis and fibrosis are emerging as risk factors for multiple
extrahepatic health conditions; however, their relationship with Alzheimer's disease …

Sedentary behaviour may increase the risk of dementia. Studying physiological effects of
sedentary behaviour on cerebral health may provide new insights into the nature of this …

Abstract Background and Study Aim: Several lines of evidence indicate that regular physical
activity has a positive impact on cognitive function. Relatively limited number of studies …

Background Coronary heart disease (CHD) is frequently associated with cognitive
impairment (CI), whereas physical exercise may improve cognition. To date, the cognitive …

Background eCohort studies offer an efficient approach for data collection. However,
eCohort studies are challenged by volunteer bias and low adherence. We designed an …

Aim Physical activity (PA) is recommended to improve glycemic control in T1D; however, the
effect of PA on distal symmetric polyneuropathy (DSPN) and cardiac autonomic function in …

Aim The current study aims to investigate the association of serum brain‐derived
neurotrophic factor (BDNF) levels with symptoms of depression in adults with and without …