Therapeutic potential of cannabis, cannabidiol, and cannabinoid-based pharmaceuticals

CA Legare, WM Raup-Konsavage, KE Vrana - Pharmacology, 2022 - karger.com
Background: There is a growing interest in the use of cannabis (and its extracts), as well as
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …

Medical use of cannabinoids

AI Fraguas-Sánchez, AI Torres-Suárez - Drugs, 2018 - Springer
Cannabinoid receptors, endocannabinoids and the enzymes responsible for their
biosynthesis and degradation constitute the endocannabinoid system. In recent decades …

Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indications

A Bilbao, R Spanagel - BMC medicine, 2022 - Springer
Background Medical cannabinoids differ in their pharmacology and may have different
treatment effects. We aimed to conduct a pharmacology-based systematic review (SR) and …

Therapeutic potential of medicinal marijuana: an educational primer for health care professionals

Y Mouhamed, A Vishnyakov, B Qorri… - Drug, healthcare and …, 2018 - Taylor & Francis
With the proposed Canadian July 2018 legalization of marijuana through the Cannabis Act,
a thorough critical analysis of the current trials on the efficacy of medicinal marijuana (MM) …

The basic science of cannabinoids

A Sideris, J Lauzadis, M Kaczocha - Anesthesia & Analgesia, 2024 - journals.lww.com
The cannabis plant has been used for centuries to manage the symptoms of various
ailments including pain. Hundreds of chemical compounds have been identified and …

A systematic review of the analgesic efficacy of cannabinoid medications in the management of acute pain

AJ Stevens, MD Higgins - Acta Anaesthesiologica Scandinavica, 2017 - Wiley Online Library
Background Cannabinergic medications have been postulated to demonstrate efficacy in
the management of pain. The aim of this systematic review was to assess the analgesic …

[HTML][HTML] Perioperative Pain and Addiction Interdisciplinary Network (PAIN): consensus recommendations for perioperative management of cannabis and cannabinoid …

KS Ladha, A McLaren-Blades, A Goel, MJ Buys… - British journal of …, 2021 - Elsevier
In many countries, liberalisation of the legislation regulating the use of cannabis has
outpaced rigorous scientific studies, and a growing number of patients presenting for …

A randomized-controlled trial of nabilone for the prevention of acute postoperative nausea and vomiting in elective surgery

DN Levin, Z Dulberg, M Gregory… - Canadian Journal of …, 2017 - search.proquest.com
Purpose Nabilone is a synthetic cannabinoid with properties that make it an appealing
candidate as a postoperative nausea and vomiting (PONV) prophylactic adjunct. Nabilone …

Cannabis, e-cigarettes and anesthesia

RSR Lynn, JL Galinkin - Current Opinion in Anesthesiology, 2020 - journals.lww.com
There is a very wide variety of cannabis products currently available, with respect to both
route of administration as well as cannabinoid content. Patients using cannabis products …

[HTML][HTML] Human pharmacokinetics and adverse effects of pulmonary and intravenous THC-CBD formulations

P Meyer, M Langos, R Brenneisen - Medical Cannabis and …, 2018 - karger.com
Background: Due to variable absorption and extensive first-pass metabolism, the
bioavailability of oral delta-9-tetra-hydrocannabinol (THC) and cannabidiol (CBD) is low …