Circulating microRNAs as potential biomarkers of infectious disease

CN Correia, NC Nalpas, KE McLoughlin… - Frontiers in …, 2017 - frontiersin.org
microRNAs (miRNAs) are a class of small non-coding endogenous RNA molecules that
regulate a wide range of biological processes by post-transcriptionally regulating gene …

Emergence of exosomal miRNAs as a diagnostic biomarker for Alzheimer's disease

V Van Giau, SSA An - Journal of the neurological sciences, 2016 - Elsevier
Alzheimer's disease (AD) is the most common progressive degenerative disorder, and is
characterized by memory loss and cognitive decline. It is a complex disorder with both …

Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations

I Prada, M Gabrielli, E Turola, A Iorio, G D'Arrigo… - Acta …, 2018 - Springer
Recent evidence indicates synaptic dysfunction as an early mechanism affected in
neuroinflammatory diseases, such as multiple sclerosis, which are characterized by chronic …

Distinct expression of the neurotoxic microRNA family let-7 in the cerebrospinal fluid of patients with Alzheimer's disease

K Derkow, R Rössling, C Schipke, C Krüger, J Bauer… - PloS one, 2018 - journals.plos.org
MicroRNAs (miRNAs) are non-coding RNAs originally involved in RNA silencing and post-
transcriptional regulation of gene expression. We have shown in previous work that the …

miRNA expression profiles in cerebrospinal fluid and blood of patients with acute ischemic stroke

SS Sørensen, AB Nygaard, MY Nielsen… - Translational stroke …, 2014 - Springer
The aims of the study were (1) to determine whether miRNAs (microRNAs) can be detected
in the cerebrospinal fluid (CSF) and blood of patients with ischemic stroke and (2) to …

[HTML][HTML] HIV-associated neurocognitive disorders: recent advances in pathogenesis, biomarkers, and treatment

A Carroll, B Brew - F1000Research, 2017 - ncbi.nlm.nih.gov
HIV-associated neurocognitive disorders (HAND) remain prevalent despite plasma viral
suppression by antiretroviral agents. In fact, the prevalence of milder subtypes of cognitive …

The MiRNA journey from theory to practice as a CNS biomarker

N Stoicea, A Du, DC Lakis, C Tipton… - Frontiers in …, 2016 - frontiersin.org
MicroRNAs (miRNAs), small nucleotide sequences that control gene transcription, have the
potential to serve an expanded function as indicators in the diagnosis and progression of …

The detection of microRNA associated with Alzheimer's disease in biological fluids using next-generation sequencing technologies

L Cheng, CYJ Quek, X Sun, SA Bellingham… - Frontiers in …, 2013 - frontiersin.org
Diagnostic tools for neurodegenerative diseases such as Alzheimer's disease (AD) currently
involve subjective neuropsychological testing and specialized brain imaging techniques …

Molecular mechanisms of fenofibrate-induced metabolic catastrophe and glioblastoma cell death

A Wilk, D Wyczechowska, A Zapata… - … and cellular biology, 2015 - Am Soc Microbiol
Fenofibrate (FF) is a common lipid-lowering drug and a potent agonist of the peroxisome
proliferator-activated receptor alpha (PPARα). FF and several other agonists of PPARα have …

HIV-associated neurocognitive impairment in the modern ART era: are we close to discovering reliable biomarkers in the setting of virological suppression?

A Bandera, L Taramasso, G Bozzi… - Frontiers in aging …, 2019 - frontiersin.org
The prevalence of the most severe forms of HIV-associated neurocognitive disorders
(HAND) is decreasing due to worldwide availability and high efficacy of antiretroviral …