Nucleic acid enzymes

R Fiammengo, A Jäschke - Current opinion in biotechnology, 2005 - Elsevier
Since the discovery of the first natural ribozyme more than 20 years ago, it has become clear
that nucleic acids are not only the static depository of genetic information, but also possess …

DNA and RNA induced enantioselectivity in chemical synthesis

G Roelfes - Molecular BioSystems, 2007 - pubs.rsc.org
One of the hallmarks of DNA and RNA structures is their elegant chirality. Using these chiral
structures to induce enantioselectivity in chemical synthesis is as enticing as it is …

Systematic characterization of 2′-deoxynucleoside-5′-triphosphate analogs as substrates for DNA polymerases by polymerase chain reaction and kinetic studies …

M Kuwahara, J Nagashima, M Hasegawa… - Nucleic Acids …, 2006 - academic.oup.com
We synthesized C5-modified analogs of 2′-deoxyuridine triphosphate and 2′-
deoxycytidine triphosphate and investigated them as substrates for PCRs using Taq, Tth …

A self-cleaving DNA enzyme modified with amines, guanidines and imidazoles operates independently of divalent metal cations (M 2+ )

M Hollenstein, CJ Hipolito, CH Lam… - Nucleic acids …, 2009 - academic.oup.com
The selection of modified DNAzymes represents an important endeavor in expanding the
chemical and catalytic properties of catalytic nucleic acids. Few examples of such exist and …

Highly enantioselective DNA-based catalysis

G Roelfes, AJ Boersma, BL Feringa - Chemical communications, 2006 - pubs.rsc.org
Highly enantioselective DNA-based catalysis - Chemical Communications (RSC Publishing)
DOI:10.1039/B516552K Royal Society of Chemistry View PDF VersionPrevious ArticleNext …

Systematic analysis of enzymatic DNA polymerization using oligo-DNA templates and triphosphate analogs involving 2′, 4′-bridged nucleosides

M Kuwahara, S Obika, J Nagashima… - Nucleic acids …, 2008 - academic.oup.com
In order to systematically analyze the effects of nucleoside modification of sugar moieties in
DNA polymerase reactions, we synthesized 16 modified templates containing 2′, 4 …

DNA-mediated enantioselective carbon-fluorine bond formation

N Shibata, H Yasui, S Nakamura, T Toru - Synlett, 2007 - thieme-connect.com
Enantioselective electrophilic fluorination of β-keto esters with Selectfluor® catalyzed by
DNA and a nonchiral ligand-Cu (II) complex is presented. The chirality transfer from DNA to …

Arginine-modified DNA aptamers that show enantioselective recognition of the dicarboxylic acid moiety of glutamic acid

K Ohsawa, T Kasamatsu, J Nagashima, K Hanawa… - Analytical …, 2008 - Springer
We have screened glutamic acid-binding aptamers from a modified DNA pool containing
arginine residues using the method of systematic evolution of ligands by exponential …

Direct PCR amplification of various modified DNAs having amino acids: convenient preparation of DNA libraries with high-potential activities for in vitro selection

M Kuwahara, K Hanawa, K Ohsawa, R Kitagata… - Bioorganic & Medicinal …, 2006 - Elsevier
We synthesized modified 2′-deoxyuridine triphosphates bearing amino acids at the C5
position and investigated their substrate properties for KOD Dash DNA polymerase during …

[图书][B] Organophosphorus Chemistry: Volume 35

CD Hall, N Bricklebank, J Van De Grampel, M Migaud… - 2006 - books.google.com
Organophosphorus Chemistry provides a comprehensive annual review of the literature.
Coverage includes phosphines and their chalcogenides, phosphonium salts, low …