Abortive Infection of Animal Cells: What Goes Wrong
A Embry, DB Gammon - Annual Review of Virology, 2024 - annualreviews.org
Even if a virus successfully binds to a cell, defects in any of the downstream steps of the viral
life cycle can preclude the production of infectious virus particles. Such abortive infections …
life cycle can preclude the production of infectious virus particles. Such abortive infections …
Promiscuous inflammasomes: the false dichotomy of RNA/DNA virus-induced inflammasome activation and pyroptosis
HL Wallace, RS Russell - Viruses, 2022 - mdpi.com
It is well-known that viruses activate various inflammasomes, which can initiate the
programmed cell death pathway known as pyroptosis, subsequently leading to cell lysis and …
programmed cell death pathway known as pyroptosis, subsequently leading to cell lysis and …
Marine algal antioxidants as potential vectors for controlling viral diseases
As the COVID-19 epidemic expands in the world, and with the previous SARS epidemic,
avian flu, Ebola and AIDS serving as a warning, biomedical and biotechnological research …
avian flu, Ebola and AIDS serving as a warning, biomedical and biotechnological research …
Ebola virus-mediated T-lymphocyte depletion is the result of an abortive infection
P Younan, RI Santos, P Ramanathan… - PLoS …, 2019 - journals.plos.org
Ebola virus (EBOV) infections are characterized by a pronounced lymphopenia that is highly
correlative with fatalities. However, the mechanisms leading to T-cell depletion remain …
correlative with fatalities. However, the mechanisms leading to T-cell depletion remain …
Ebola virus Bayesian machine learning models enable new in vitro leads
M Anantpadma, T Lane, KM Zorn, MA Lingerfelt… - ACS …, 2019 - ACS Publications
We have previously described the first Bayesian machine learning models from FDA-
approved drug screens, for identifying compounds active against the Ebola virus (EBOV) …
approved drug screens, for identifying compounds active against the Ebola virus (EBOV) …
Characterization of an air-liquid interface primary human vaginal epithelium to study Ebola virus infection and testing of antivirals
O Escaffre, V Popov, E Hager, AN Freiberg - Antiviral research, 2023 - Elsevier
Ebola virus (EBOV) is the causative agent of the often-fatal Ebola virus disease (EVD)
characterized by hemorrhagic fever in humans and non-human primates. Sexual …
characterized by hemorrhagic fever in humans and non-human primates. Sexual …
Decoding the enigma of antiviral crisis: Does one target molecule regulate all?
Disease fatality associated with Ebola, SARS-CoV and dengue infections in humans is
attributed to a cytokine storm that is triggered by excessive pro-inflammatory responses …
attributed to a cytokine storm that is triggered by excessive pro-inflammatory responses …
PET imaging of TSPO expression in immune cells can assess organ-level pathophysiology in high-consequence viral infections
S Shah, S Sinharay, R Patel… - Proceedings of the …, 2022 - National Acad Sciences
Ebola virus (EBOV) disease is characterized by lymphopenia, breach in vascular integrity,
cytokine storm, and multiorgan failure. The pathophysiology of organ involvement, however …
cytokine storm, and multiorgan failure. The pathophysiology of organ involvement, however …
T-cell response to viral hemorrhagic fevers
F Perdomo-Celis, MS Salvato, S Medina-Moreno… - Vaccines, 2019 - mdpi.com
Viral hemorrhagic fevers (VHF) are a group of clinically similar diseases that can be caused
by enveloped RNA viruses primarily from the families Arenaviridae, Filoviridae …
by enveloped RNA viruses primarily from the families Arenaviridae, Filoviridae …
Extracellular vesicle storm during the course of Ebola virus infection in primates
Introduction Ebola virus (EBOV) is an RNA virus of the Filoviridae family that is responsible
for outbreaks of hemorrhagic fevers in primates with a lethality rate as high as 90%. EBOV …
for outbreaks of hemorrhagic fevers in primates with a lethality rate as high as 90%. EBOV …