Bioactive materials promote wound healing through modulation of cell behaviors

R Li, K Liu, X Huang, D Li, J Ding, B Liu… - Advanced …, 2022 - Wiley Online Library
Skin wound repair is a multistage process involving multiple cellular and molecular
interactions, which modulate the cell behaviors and dynamic remodeling of extracellular …

Macrocyclic supramolecular assemblies based on hyaluronic acid and their biological applications

Z Liu, W Lin, Y Liu - Accounts of Chemical Research, 2022 - ACS Publications
Conspectus Hyaluronic acid (HA), which contains multiple carboxyl, hydroxyl, and
acetylamino groups and is an agent that targets tumors, has drawn great attention in …

High and low molecular weight hyaluronic acid differentially influence macrophage activation

JE Rayahin, JS Buhrman, Y Zhang… - ACS biomaterials …, 2015 - ACS Publications
Macrophages exhibit phenotypic diversity permitting wide-ranging roles in maintaining
physiologic homeostasis. Hyaluronic acid, a major glycosaminoglycan of the extracellular …

TSG-6: A multifunctional protein with anti-inflammatory and tissue-protective properties

AJ Day, CM Milner - Matrix Biology, 2019 - Elsevier
Tumor necrosis factor-(TNF) stimulated gene-6 (TSG-6) is an inflammation-associated
secreted protein that has been implicated as having important and diverse tissue protective …

Hyaluronan, a crucial regulator of inflammation

AC Petrey, CA de la Motte - Frontiers in immunology, 2014 - frontiersin.org
Hyaluronan (HA), a major component of the extracellular matrix (ECM), plays a key role in
regulating inflammation. Inflammation is associated with accumulation and turnover of HA …

Applications of the amniotic membrane in tissue engineering and regeneration: the hundred-year challenge

H Elkhenany, A El-Derby, M Abd Elkodous… - Stem Cell Research & …, 2022 - Springer
The amniotic membrane (Amnio-M) has various applications in regenerative medicine. It
acts as a highly biocompatible natural scaffold and as a source of several types of stem cells …

The inter-α-trypsin inhibitor family: Versatile molecules in biology and pathology

MS Lord, J Melrose, AJ Day… - … of Histochemistry & …, 2020 - journals.sagepub.com
Inter-α-trypsin inhibitor (IαI) family members are ancient and unique molecules that have
evolved over several hundred million years of vertebrate evolution. IαI is a complex …

HC-HA/PTX3 purified from amniotic membrane as novel regenerative matrix: insight into relationship between inflammation and regeneration

SCG Tseng - Investigative ophthalmology & visual science, 2016 - iovs.arvojournals.org
Purpose: Human limbal palisade of Vogt is an ideal model for studying and practicing
regenerative medicine due to their accessibility. Nonresolving inflammation is a common …

The role of an IL-10/hyaluronan axis in dermal wound healing

KL Singampalli, S Balaji, X Wang, UM Parikh… - Frontiers in cell and …, 2020 - frontiersin.org
Scar formation is the typical endpoint of postnatal dermal wound healing, which affects more
than 100 million individuals annually. Not only do scars cause a functional burden by …

Comparison of cryopreserved amniotic membrane and umbilical cord tissue with dehydrated amniotic membrane/chorion tissue

M Cooke, EK Tan, C Mandrycky, H He… - Journal of Wound …, 2014 - magonlinelibrary.com
Objective: To evaluate how the different processing methods cryopreservation and
dehydration affect the structural integrity and biological composition of key signalling …