Anticholinergic burden quantified by anticholinergic risk scales and adverse outcomes in older people: a systematic review

MS Salahudeen, SB Duffull, PS Nishtala - BMC geriatrics, 2015 - Springer
Background The cumulative effect of taking multiple medicines with anticholinergic
properties termed as anticholinergic burden can adversely impact cognition, physical …

Effect of medications with anti-cholinergic properties on cognitive function, delirium, physical function and mortality: a systematic review

C Fox, T Smith, I Maidment, WY Chan, N Bua… - Age and …, 2014 - academic.oup.com
Objectives: to determine the effect of drugs with anti-cholinergic properties on relevant
health outcomes. Design: electronic published and unpublished literature/trial registries …

Anticholinergic drugs and negative outcomes in the older population: from biological plausibility to clinical evidence

A Collamati, AM Martone, A Poscia, V Brandi… - Aging clinical and …, 2016 - Springer
The use of medication with anticholinergic properties is widespread among older subjects.
Many drugs of common use such as antispasmodics, bronchodilators, antiarrhythmics …

Anticholinergic drug burden tools/scales and adverse outcomes in different clinical settings: a systematic review of reviews

TJ Welsh, V van der Wardt, G Ojo, AL Gordon… - Drugs & aging, 2018 - Springer
Background Cumulative anticholinergic exposure (anticholinergic burden) has been linked
to a number of adverse outcomes. To conduct research in this area, an agreed approach to …

Anticholinergic medication: related dry mouth and effects on the salivary glands

S Arany, DT Kopycka-Kedzierawski, TV Caprio… - Oral surgery, oral …, 2021 - Elsevier
Objective Salivary glands are among the most sensitive target organs of medications with
anticholinergic (AC) properties, interrupting the neural stimulation of saliva secretion and …

Comparison of anticholinergic risk scales and associations with adverse health outcomes in older people

MS Salahudeen, SN Hilmer… - Journal of the American …, 2015 - Wiley Online Library
Objectives To investigate whether anticholinergic burden scores from nine published
anticholinergic scales are associated with adverse health outcomes, including hospital …

Quality of anticholinergic burden scales and their impact on clinical outcomes: a systematic review

A Lisibach, V Benelli, MG Ceppi… - European journal of …, 2021 - Springer
Purpose Older people are at risk of anticholinergic side effects due to changes affecting drug
elimination and higher sensitivity to drug's side effects. Anticholinergic burden scales (ABS) …

Systematic review on the use of anticholinergic scales in poly pathological patients

AM Villalba-Moreno, ER Alfaro-Lara… - Archives of gerontology …, 2016 - Elsevier
Purpose Anticholinergic drugs may increase the risk of cognitive and functional disorders in
older patients. There are anticholinergic scales on which said risk is estimated. The …

Anticholinergic drug burden in older people's brain–how well is it measured?

H Kersten, TB Wyller - Basic & clinical pharmacology & …, 2014 - Wiley Online Library
Concurrent use of several drugs with potential anticholinergic properties is highly prevalent
in the elderly. Methods to determine the overall anticholinergic drug burden have been …

Tools for assessment of the appropriateness of prescribing and association with patient-related outcomes: a systematic review

N Masnoon, S Shakib, L Kalisch-Ellett, GE Caughey - Drugs & aging, 2018 - Springer
Background There are tools and criteria in the literature aimed at distinguishing between
appropriate and inappropriate medicines use. However, many have not been externally …