Hydrogel is a type of versatile platform with various biomedical applications after rational
structure and functional design that leverages on material engineering to modulate its …

Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …

Hydrogel scaffolds that can repair or regrow damaged biological tissue have great potential
for the treatment of injury and disease. These biomaterials are widely used in the tissue …

Collagen is the oldest and most abundant extracellular matrix protein that has found many
applications in food, cosmetic, pharmaceutical, and biomedical industries. First, an overview …

Collagen hydrogels are among​ the most well-studied platforms for drug delivery and in situ
tissue engineering, thanks to their low cost, low immunogenicity, versatility, biocompatibility …

Hydrogels are one of the most commonly explored classes of biomaterials. Their chemical
and structural versatility has enabled their use across a wide range of applications, including …

The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Organoids are 3D cell culture systems that mimic some of the structural and functional
characteristics of an organ. Organoid cultures provide the opportunity to study organ-level …

The aberrant mechanical microenvironment in degenerated tissues induces misdirection of
cell fate, making it challenging to achieve efficient endogenous regeneration. Herein, a …

Natural tissues and organs exhibit an array of spatial gradients, from the polarized neural
tube during embryonic development to the osteochondral interface present at articulating …