Although the anti-diabetic activity of cinnamic acid, a pure compound from cinnamon, has
been reported but its mechanism (s) is not yet clear. The present study was designed to …

Conflicting results have been reported on segmental differences in expression of P-
glycoprotein (P-gp) along the small intestine of animals and humans. In this study, we …

The present work aimed to re-assess the bioavailability enhancement potential of fulvic acid
(FA). Carbamazepine (CBZ) and peat were used as a model drug and FA source …

Poor aqueous solubility and bioavailability of the drugs is the major impediment in the field
of drug development. Amongst the various solubility enhancing techniques, complexation of …

Objective: The present work studied the pharmacokinetic drug interactions between
fluvoxamine and pioglitazone in healthy and disease rats following single and multiple …

Objective To investigate the anti-hyperglycemic and peripheral glucose utilization activity of
petroleum ether extract of leafs of Streblus asper (SAPE) as well as to find out the …

Background: Gliclazide is a widely used drug for the treatment of type 2 diabetes.
Retrospective studies shows that diabetics are at increased risk of suffering severe …

Purpose: Piperine, the major bioactive compound from black pepper, has been associated
with beneficial effects on central nervous system (CNS), including anti-epileptic effect, in …

The resistance to antiepileptic drugs (AEDs) remains a major unsolved therapeutic problem,
which affects 30-40% of patients with epilepsy. The overexpression of multidrug efflux …

Background: Diabetes mellitus is a major public health problem with many complications.
The Global Burden of Diabetes Study has projected that there will be a 122% increase in the …