A compendium of single extracellular vesicle flow cytometry
JA Welsh, GJA Arkesteijn, M Bremer… - Journal of …, 2023 - Wiley Online Library
Flow cytometry (FCM) offers a multiparametric technology capable of characterizing single
extracellular vesicles (EVs). However, most flow cytometers are designed to detect cells …
extracellular vesicles (EVs). However, most flow cytometers are designed to detect cells …
[HTML][HTML] Role of neutrophils, platelets, and extracellular vesicles and their interactions in COVID‐19‐associated thrombopathy
The COVID‐19 pandemic extended all around the world causing millions of deaths. In
addition to acute respiratory distress syndrome, many patients with severe COVID‐19 …
addition to acute respiratory distress syndrome, many patients with severe COVID‐19 …
Towards defining reference materials for measuring extracellular vesicle refractive index, epitope abundance, size and concentration
JA Welsh, E van der Pol, BA Bettin… - Journal of …, 2020 - Taylor & Francis
Accurate characterization of extracellular vesicles (EVs) is critical to explore their diagnostic
and therapeutic applications. As the EV research field has developed, so too have the …
and therapeutic applications. As the EV research field has developed, so too have the …
[HTML][HTML] Extracellular vesicles and thrombosis: update on the clinical and experimental evidence
K Zifkos, C Dubois, K Schäfer - International Journal of Molecular …, 2021 - mdpi.com
Extracellular vesicles (EVs) compose a heterogenous group of membrane-derived particles,
including exosomes, microvesicles and apoptotic bodies, which are released into the …
including exosomes, microvesicles and apoptotic bodies, which are released into the …
[HTML][HTML] Removal of platelets from blood plasma to improve the quality of extracellular vesicle research
Background Blood plasma is commonly used for biomarker research of extracellular
vesicles (EVs). Removing all cells prior to analysis of EVs is essential. Objectives We …
vesicles (EVs). Removing all cells prior to analysis of EVs is essential. Objectives We …
The role of platelet P2Y12 receptors in inflammation
WAE Parker, RF Storey - British Journal of Pharmacology, 2024 - Wiley Online Library
Inflammation is a complex pathophysiological process underlying many clinical conditions.
Platelets contribute to the thrombo‐inflammatory response. Platelet P2Y12 receptors amplify …
Platelets contribute to the thrombo‐inflammatory response. Platelet P2Y12 receptors amplify …
[HTML][HTML] Extracellular vesicles as drivers of immunoinflammation in atherothrombosis
Atherosclerotic cardiovascular disease is the leading cause of morbidity and mortality all
over the world. Extracellular vesicles (EVs), small lipid-bilayer membrane vesicles released …
over the world. Extracellular vesicles (EVs), small lipid-bilayer membrane vesicles released …
[HTML][HTML] Circulating extracellular vesicles as biomarkers and drug delivery vehicles in cardiovascular diseases
Extracellular vesicles (EVs) are composed of a lipid bilayer containing transmembrane and
soluble proteins. Subtypes of EVs include ectosomes (microparticles/microvesicles) …
soluble proteins. Subtypes of EVs include ectosomes (microparticles/microvesicles) …
The role of miRNAs in regulation of platelet activity and related diseases-a bioinformatic analysis
Z Wicik, P Czajka, C Eyileten, A Fitas, M Wolska… - Platelets, 2022 - Taylor & Francis
MicroRNAs (miRNAs) are small, non-coding RNAs, able to regulate cellular functions by
induction of mRNA degradation and post-transcriptional repression of gene expression …
induction of mRNA degradation and post-transcriptional repression of gene expression …
Fluorescence and light scatter calibration allow comparisons of small particle data in standard units across different flow cytometry platforms and detector settings
Flow cytometers have been utilized for the analysis of submicron‐sized particles since the
late 1970s. Initially, virus analyses preceded extracellular vesicle (EV), which began in the …
late 1970s. Initially, virus analyses preceded extracellular vesicle (EV), which began in the …