Effects of diet on brain plasticity in animal and human studies: mind the gap

T Murphy, GP Dias, S Thuret - Neural plasticity, 2014 - Wiley Online Library
Dietary interventions have emerged as effective environmental inducers of brain plasticity.
Among these dietary interventions, we here highlight the impact of caloric restriction (CR: a …

The effects of dietary restriction on oxidative stress in rodents

ME Walsh, Y Shi, H Van Remmen - Free Radical Biology and Medicine, 2014 - Elsevier
Oxidative stress is observed during aging and in numerous age-related diseases. Dietary
restriction (DR) is a regimen that protects against disease and extends life span in multiple …

Calorie restriction in rodents: Caveats to consider

DK Ingram, R de Cabo - Ageing research reviews, 2017 - Elsevier
The calorie restriction paradigm has provided one of the most widely used and most useful
tools for investigating mechanisms of aging and longevity. By far, rodent models have been …

Late-onset intermittent fasting dietary restriction as a potential intervention to retard age-associated brain function impairments in male rats

R Singh, D Lakhanpal, S Kumar, S Sharma, H Kataria… - Age, 2012 - Springer
Lifelong dietary restriction (DR) is known to have many potential beneficial effects on brain
function as well as delaying the onset of neurological diseases. In the present investigation …

Caloric restriction: beneficial effects on brain aging and Alzheimer's disease

C Van Cauwenberghe, C Vandendriessche, C Libert… - Mammalian …, 2016 - Springer
Dietary interventions such as caloric restriction (CR) extend lifespan and health span.
Recent data from animal and human studies indicate that CR slows down the aging process …

Nutrition, food and diet in health and longevity: we eat what we are

SIS Rattan, G Kaur - Nutrients, 2022 - mdpi.com
Nutrition generally refers to the macro-and micro-nutrients essential for survival, but we do
not simply eat nutrition. Instead, we eat animal-and plant-based foods without always being …

[HTML][HTML] Decreased mTOR signalling reduces mitochondrial ROS in brain via accumulation of the telomerase protein TERT within mitochondria

S Miwa, R Czapiewski, T Wan, A Bell, KN Hill… - Aging (Albany …, 2016 - ncbi.nlm.nih.gov
Telomerase in its canonical function maintains telomeres in dividing cells. In addition, the
telomerase protein TERT has non-telomeric functions such as shuttling to mitochondria …

Intermittent fasting results in tissue-specific changes in bioenergetics and redox state

B Chausse, MA Vieira-Lara, AB Sanchez… - PLoS …, 2015 - journals.plos.org
Intermittent fasting (IF) is a dietary intervention often used as an alternative to caloric
restriction (CR) and characterized by 24 hour cycles alternating ad libitum feeding and …

Role of membrane Hsp70 in radiation sensitivity of tumor cells

N Murakami, A Kühnel, TE Schmid, K Ilicic, S Stangl… - Radiation …, 2015 - Springer
Background The major stress-inducible heat shock protein 70 (Hsp70) is frequently
overexpressed in the cytosol and integrated in the plasma membrane of tumor cells via lipid …

Long-Term l-Serine Administration Reduces Food Intake and Improves Oxidative Stress and Sirt1/NFκB Signaling in the Hypothalamus of Aging Mice

X Zhou, H Zhang, L He, X Wu, Y Yin - Frontiers in Endocrinology, 2018 - frontiersin.org
Serine has recently been shown to reduce oxidative stress and inflammation, which, when
occurring in the hypothalamus, contribute to age-related obesity. To explore whether long …