Quantitative analysis can potentially improve the accuracy and consistency of 18F-FDG PET,
particularly for the assessment of tumor response to treatment. Although not without …

Modern radiation therapy is delivered with great precision, in part by relying on high-
resolution multidimensional anatomic imaging to define targets in space and time. The …

Purpose There is a clinical need for agents that target glioma cells for non-invasive and
intraoperative imaging to guide therapeutic intervention and improve the prognosis of …

Abstract Background. Mibefradil (MIB), previously approved for treatment of hypertension, is
a selective T-type calcium channel blocker with preclinical activity in high-grade gliomas …

Imaging plays a central role in evaluating responses to therapy in neuro-oncology patients.
The advancing clinical use of immunotherapies has demonstrated that treatment-related …

Purpose Response evaluation in patients with glioblastoma after chemoradiotherapy is
challenging due to progressive, contrast-enhancing lesions on MRI that do not reflect true …

Multiple myeloma (MM) is a plasma cell disorder, characterized by clonal proliferation of
malignant plasma cells in the bone marrow. Bone disease is the most frequent feature and …

Radiotracers, or radiopharmaceuticals, are bioactive molecules tagged with a radionuclide
used for diagnostic imaging or radiotherapy and, when a positron-emitting radionuclide is …

Background Despite the significant upgrading in recent years of the role of 18 F-FDG
PET/CT in multiple myeloma (MM) diagnostics, there is a still unmet need for myeloma …

Background The molecular diagnosis of gliomas such as isocitrate dehydrogenase (IDH)
status (wild-type [wt] or mutation [mut]) is especially important in the 2016 World Health …