The SARS‐CoV‐2 main protease (Mpro): Structure, function, and emerging therapies for COVID‐19

Q Hu, Y Xiong, GH Zhu, YN Zhang, YW Zhang… - MedComm, 2022 - Wiley Online Library
The main proteases (Mpro), also termed 3‐chymotrypsin‐like proteases (3CLpro), are a
class of highly conserved cysteine hydrolases in β‐coronaviruses. Increasing evidence has …

Natural product-derived phytochemicals as potential agents against coronaviruses: A review

JS Mani, JB Johnson, JC Steel, DA Broszczak… - Virus research, 2020 - Elsevier
Coronaviruses are responsible for a growing economic, social and mortality burden, as the
causative agent of diseases such as severe acute respiratory syndrome (SARS), Middle …

[HTML][HTML] Traditional Chinese medicine in COVID-19

M Lyu, G Fan, G Xiao, T Wang, D Xu, J Gao… - … Pharmaceutica Sinica B, 2021 - Elsevier
COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has spread across the globe, posing an enormous threat to public health and safety …

Potential roles of medicinal plants for the treatment of viral diseases focusing on COVID‐19: A review

B Adhikari, BP Marasini, B Rayamajhee… - Phytotherapy …, 2021 - Wiley Online Library
The whole world is entangled by the coronavirus disease (COVID‐19) pandemic caused by
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), people are dying in …

[HTML][HTML] Natural therapeutics and nutraceuticals for lung diseases: traditional significance, phytochemistry, and pharmacology

MM Rahman, S Bibi, MS Rahaman, F Rahman… - Biomedicine & …, 2022 - Elsevier
Background Lung diseases including chronic obstructive pulmonary disease (COPD),
infections like influenza, acute respiratory distress syndrome (ARDS), asthma and …

Structure and function of SARS-CoV and SARS-CoV-2 main proteases and their inhibition: A comprehensive review

X Li, Y Song - European Journal of Medicinal Chemistry, 2023 - Elsevier
Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) identified in 2003
infected∼ 8000 people in 26 countries with 800 deaths, which was soon contained and …

Natural products for COVID‐19 prevention and treatment regarding to previous coronavirus infections and novel studies

M Boozari, H Hosseinzadeh - Phytotherapy Research, 2021 - Wiley Online Library
Recently, the novel life‐threatening coronavirus infection (COVID‐19) was reported at the
end of 2019 in Wuhan, China, and spread throughout the world in little time. The effective …

[HTML][HTML] In silico screening of Chinese herbal medicines with the potential to directly inhibit 2019 novel coronavirus

D Zhang, K Wu, X Zhang, S Deng, B Peng - Journal of integrative medicine, 2020 - Elsevier
Objective In this study we execute a rational screen to identify Chinese medical herbs that
are commonly used in treating viral respiratory infections and also contain compounds that …

Drug development and medicinal chemistry efforts toward SARS‐coronavirus and Covid‐19 therapeutics

AK Ghosh, M Brindisi, D Shahabi… - …, 2020 - Wiley Online Library
The COVID‐19 pandemic caused by SARS‐CoV‐2 infection is spreading at an alarming
rate and has created an unprecedented health emergency around the globe. There is no …

Plants metabolites: possibility of natural therapeutics against the COVID-19 pandemic

FR Bhuiyan, S Howlader, T Raihan, M Hasan - Frontiers in medicine, 2020 - frontiersin.org
COVID-19, a disease induced by SARS-CoV-2 (Severe Acute Respiratory Syndrome
Coronavirus-2), has been the cause of a worldwide pandemic. Though extensive research …