Multicellular tumor spheroid models (MCTS) are often coined as 3D in vitro models that can
mimic the microenvironment of tissues. MCTS have gained increasing interest in the nano …

Tumor-targeted drug delivery systems are promising for their advantages in enhanced tumor
accumulation and reduced toxicity towards normal organs. However, few nanomedicines …

Quantitative studies of the long-term fate of iron oxide nanoparticles inside cells, a
prerequisite for regenerative medicine applications, are hampered by the lack of suitable …

With the rapid development of biotechnology and nanomedicine, extensive research has
focused on the investigations of delivering large-cargo molecules using nanoparticles …

Compared to conventional treatments, gene therapy offers a variety of advantages for
cancer treatment including high potency and specificity, low off-target toxicity, and delivery of …

Magnetic particle imaging (MPI) is an emerging biomedical imaging technology that allows
the direct quantitative mapping of the spatial distribution of superparamagnetic iron oxide …

Metastasis is one of the most important factors that lead to poor prognosis in cancer patients,
and effective suppression of the growth of primary cancer cells in a metastatic site is …

Nanomedicine has emerged as a promising therapeutic approach, but its translation to the
clinic has been hindered by the lack of cellular models to anticipate how tumor cells will …

The growth and breadth of nanoparticle (NP) research now encompasses many scientific
and technologic fields, which has driven the want to control NP dimensions, structures and …

A variety of engineered nanoparticles, including lipid nanoparticles, polymer nanoparticles,
gold nanoparticles, and biomimetic nanoparticles, have been studied as delivery vehicles …