Genetic control strategies such as the sterile insect technique have successfully fought
insect pests worldwide. The CRISPR (clustered regularly interspaced short palindromic …

Population-scale genome modification can alter the composition or fate of wild populations.
Synthetic gene drives provide one set of tools, but their use is complicated by scientific …

Abstract Spotted wing Drosophila (Drosophila suzukii Matsumura, or SWD), an insect pest of
soft-skinned fruits native to East Asia, has rapidly spread worldwide in the past 15 years …

Background Methods to suppress pest insect populations using genetic constructs and
repeated releases of male homozygotes have recently been shown to be an attractive …

The Drosophila suzukii invasion of western countries has created an immense agricultural
and economic threat to crop production. Despite many attempts to suppress its population …

Invasive freshwater mussels, such as the zebra (Dreissena polymorpha), quagga
(Dreissena rostriformis bugensis), and golden (Limnoperna fortunei) mussel have spread …

The sterile insect technique (SIT) is a well-established and environmentally benign method
for population control. Identifying genes that regulate insect fertility while preserving growth …

Background Threshold-dependent gene drives (TDGDs) could be used to spread desirable
traits through a population, and are likely to be less invasive and easier to control than …

Mosquitoes are vectors for a number of infectious diseases. Only females feed on blood to
provision for their embryos and, in doing so, transmit pathogens to the associated vertebrate …

Optimized dCas9 programmable transcriptional activators for plants - PMC Skip to main content
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