The cell surface display of peptides by MHC class I molecules to lymphocytes provides the
host with an important surveillance mechanism to protect against invading pathogens …

The versatility of ubiquitin in regulating protein function and cell behaviour through post-
translational protein modification makes it a particularly attractive target for viruses. Here we …

Efficient genetic modification of herpesviruses such as Kaposi's sarcoma-associated
herpesvirus (KSHV) has come to rely on bacterial artificial chromosome (BAC) technology …

Severe cases of SARS‐CoV‐2 infection are characterized by hypercoagulopathies and
systemic endotheliitis of the lung microvasculature. The dynamics of vascular damage, and …

ABSTRACT K3/MIR1 and K5/MIR2 of Kaposi's sarcoma-associated herpesvirus (KSHV) are
viral members of the membrane-associated RING-CH (MARCH) ubiquitin ligase family and …

Kaposi's sarcoma-associated herpesvirus (KSHV) is a double-stranded DNA virus with the
capacity to establish life-long latent infection. During latent infection, the viral genome …

Mitochondria-associated membranes (MAMs) are the organellar contact sites between
mitochondria and the endoplasmic reticulum (ER), and recent studies demonstrated that …

Immunomodulators of pathogens frequently affect multiple cellular targets, thus preventing
recognition by different immune cells. For instance, the K5 modulator of immune recognition …

Natural killer (NK) cells are important early mediators of host immunity to viral infections. The
NK activatory receptors NKG2D and NKp80, both C-type lectin-like homodimeric receptors …

The MHC class I antigen presentation pathway enables cells infected with intracellular
pathogens to signal the presence of the invader to the immune system. Cytotoxic T …