Digital medicine and the curse of dimensionality

V Berisha, C Krantsevich, PR Hahn, S Hahn… - NPJ digital …, 2021 - nature.com
Digital health data are multimodal and high-dimensional. A patient's health state can be
characterized by a multitude of signals including medical imaging, clinical variables …

I tried a bunch of things: The dangers of unexpected overfitting in classification of brain data

M Hosseini, M Powell, J Collins… - Neuroscience & …, 2020 - Elsevier
Abstract Machine learning has enhanced the abilities of neuroscientists to interpret
information collected through EEG, fMRI, and MEG data. With these powerful techniques …

A Systematic Evaluation of Machine Learning–Based Biomarkers for Major Depressive Disorder

NR Winter, J Blanke, R Leenings, J Ernsting… - JAMA …, 2024 - jamanetwork.com
Importance Biological psychiatry aims to understand mental disorders in terms of altered
neurobiological pathways. However, for one of the most prevalent and disabling mental …

Reproducibility in neuroimaging analysis: challenges and solutions

R Botvinik-Nezer, TD Wager - Biological Psychiatry: Cognitive …, 2023 - Elsevier
Recent years have marked a renaissance in efforts to increase research reproducibility in
psychology, neuroscience, and related fields. Reproducibility is the cornerstone of a solid …

Using graph convolutional network to characterize individuals with major depressive disorder across multiple imaging sites

K Qin, D Lei, WHL Pinaya, N Pan, W Li, Z Zhu… - …, 2022 - thelancet.com
Background Establishing objective and quantitative neuroimaging biomarkers at individual
level can assist in early and accurate diagnosis of major depressive disorder (MDD) …

Modern methods of diagnostics and treatment of neurodegenerative diseases and depression

N Shusharina, D Yukhnenko, S Botman, V Sapunov… - Diagnostics, 2023 - mdpi.com
This paper discusses the promising areas of research into machine learning applications for
the prevention and correction of neurodegenerative and depressive disorders. These two …

Inconsistent partitioning and unproductive feature associations yield idealized radiomic models

M Gidwani, K Chang, JB Patel, KV Hoebel, SR Ahmed… - Radiology, 2022 - pubs.rsna.org
Background Radiomics is the extraction of predefined mathematic features from medical
images for the prediction of variables of clinical interest. While some studies report …

Time-sensitive changes in the maternal brain and their influence on mother-child attachment

S Nehls, E Losse, C Enzensberger, T Frodl… - Translational …, 2024 - nature.com
Pregnancy and the postpartum period are characterized by an increased neuroplasticity in
the maternal brain. To explore the dynamics of postpartum changes in gray matter volume …

Evaluation of risk of bias in neuroimaging-based artificial intelligence models for psychiatric diagnosis: a systematic review

Z Chen, X Liu, Q Yang, YJ Wang, K Miao… - JAMA network …, 2023 - jamanetwork.com
Importance Neuroimaging-based artificial intelligence (AI) diagnostic models have
proliferated in psychiatry. However, their clinical applicability and reporting quality (ie …

Sampling inequalities affect generalization of neuroimaging-based diagnostic classifiers in psychiatry

Z Chen, B Hu, X Liu, B Becker, SB Eickhoff, K Miao… - BMC medicine, 2023 - Springer
Background The development of machine learning models for aiding in the diagnosis of
mental disorder is recognized as a significant breakthrough in the field of psychiatry …