Immune tolerance and the prevention of autoimmune diseases essentially depend on thymic tissue homeostasis

F Shirafkan, L Hensel, K Rattay - Frontiers in Immunology, 2024 - frontiersin.org
The intricate balance of immune reactions towards invading pathogens and immune
tolerance towards self is pivotal in preventing autoimmune diseases, with the thymus playing …

The partitioning of TCR repertoires by thymic selection

WL Lo, ES Huseby - Journal of Experimental Medicine, 2024 - rupress.org
αβ T cells are critical components of the adaptive immune system; they maintain tissue and
immune homeostasis during health, provide sterilizing immunity after pathogen infection …