DNA and RNA contain, next to the four canonical nucleobases, a number of modified
nucleosides that extend their chemical information content. RNA is particularly rich in …

Micronutrients from the diet and gut microbiota are essential to human health and wellbeing.
Arguably, among the most intriguing and enigmatic of these micronutrients is queuine, an …

This volume is a timely and comprehensive description of the many facets of DNA and RNA
modification-editing processes and to some extent repair mechanisms. Each chapter offers …

Riboswitches are RNA regulatory elements that govern gene expression by recognition of
small molecule ligands via a high affinity aptamer domain. Molecular recognition can lead to …

Riboswitches are structured non-coding RNAs often located upstream of essential genes in
bacterial messenger RNAs. Such RNAs regulate expression of downstream genes by …

Antimicrobial resistance develops as a major problem in infectious diseases treatment.
While antibiotic resistance mechanisms are usually studied using lethal antibiotic doses …

Riboswitches regulate downstream gene expression by binding cellular metabolites.
Regulation of translation initiation by riboswitches is posited to occur by metabolite …

Transfer RNA (tRNA) from all organisms on this planet contains modified nucleosides, which
are derivatives of the four major nucleosides. tRNA from Escherichia coli/Salmonella …

Two-component signal transduction systems (TCSs) are widespread types of protein
machinery, typically consisting of a histidine kinase membrane sensor and a cytoplasmic …

The modified nucleotide queuosine (Q) is almost universally found in the anticodon wobble
position of specific tRNAs. In many bacteria, biosynthesis of Q is modulated by a class of …