The ability to design nanostructures with arbitrary shapes and controllable motions has
made DNA nanomaterials used widely to construct diverse nanomachines with various …

Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

The cytoskeleton is an essential component of a cell. It controls the cell shape, establishes
the internal organization, and performs vital biological functions. Building synthetic …

INTRODUCTION Since the 1980s, the design and synthesis of molecular machines has
been identified as a grand challenge for molecular engineering. Robots are an important …

Synthetic DNA motors have great potential to mimic natural protein motors in cells but the
operation of synthetic DNA motors in living cells remains challenging and has not been …

Bioinspired out-of-equilibrium systems will set the scene for the next generation of molecular
materials with active, adaptive, autonomous, emergent and intelligent behavior. Indeed life …

DNA‐based machines have attracted rapidly growing interest owing to their potential in drug
delivery, biocomputing, and diagnostic applications. Herein, we report a type of exonuclease …

With the ultimate aim to construct a living cell, bottom-up synthetic biology strives to
reconstitute cellular phenomena in vitro–disentangled from the complex environment of a …

MicroRNA (miRNA) is a class of endogenous, noncoding RNA with a typical length of 19−
23 nucleotides (nt). 1− 3 miRNA regulate the expression of specific genes by binding to …

Enzymes play a crucial role in many biological processes which require harnessing and
converting free chemical energy into kinetic forces in order to accomplish tasks. Enzymes …