The impact of maternal high-fat diet on offspring neurodevelopment

G Urbonaite, A Knyzeliene, FS Bunn… - Frontiers in …, 2022 - frontiersin.org
A maternal high-fat diet affects offspring neurodevelopment with long-term consequences on
their brain health and behavior. During the past three decades, obesity has rapidly …

Schizophrenia-relevant behavioral testing in rodent models: a uniquely human disorder?

CM Powell, T Miyakawa - Biological psychiatry, 2006 - Elsevier
Animal models are extremely useful tools in defining pathogenesis and treatment of human
disease. Creating adequate animal models of complex neuropsychiatric disorders such as …

T cell deficiency leads to cognitive dysfunction: implications for therapeutic vaccination for schizophrenia and other psychiatric conditions

J Kipnis, H Cohen, M Cardon, Y Ziv… - Proceedings of the …, 2004 - National Acad Sciences
The effects of the adaptive immune system on the cognitive performance and abnormal
behaviors seen in mental disorders such as schizophrenia have never been documented …

Evaluation of animal models of neurobehavioral disorders

FJ van der Staay, SS Arndt, RE Nordquist - Behavioral and Brain …, 2009 - Springer
Animal models play a central role in all areas of biomedical research. The process of animal
model building, development and evaluation has rarely been addressed systematically …

Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia

JW Young, SB Powell, V Risbrough, HM Marston… - Pharmacology & …, 2009 - Elsevier
Cognitive deficits in schizophrenia are among the core symptoms of the disease, correlate
with functional outcome, and are not well treated with current antipsychotic therapies. In …

The neuregulin-1 receptor erbB4 controls glutamatergic synapse maturation and plasticity

B Li, RS Woo, L Mei, R Malinow - Neuron, 2007 - cell.com
Summary Neuregulin-1 (NRG1) signaling participates in numerous neurodevelopmental
processes. Through linkage analysis, nrg1 has been associated with schizophrenia …

Prevention and treatment of drug addiction by environmental enrichment

M Solinas, N Thiriet, C Chauvet, M Jaber - Progress in neurobiology, 2010 - Elsevier
Environmental enrichment (EE) has been shown to have powerful beneficial effects on a
variety of physiological and pathological processes. Accumulating evidence indicates that …

Toxoplasma gondii infection, from predation to schizophrenia: can animal behaviour help us understand human behaviour?

JP Webster, M Kaushik, GC Bristow… - Journal of …, 2013 - journals.biologists.com
We examine the role of the protozoan Toxoplasma gondii as a manipulatory parasite and
question what role study of infections in its natural intermediate rodent hosts and other …

Smoking, nicotine and neuropsychiatric disorders

P Dome, J Lazary, MP Kalapos, Z Rihmer - Neuroscience & Biobehavioral …, 2010 - Elsevier
Tobacco smoking is an extremely addictive and harmful form of nicotine (NIC) consumption,
but unfortunately also the most prevalent. Although disproportionately high frequencies of …

Environmental enrichment during early stages of life reduces the behavioral, neurochemical, and molecular effects of cocaine

M Solinas, N Thiriet, RE Rawas, V Lardeux… - …, 2009 - nature.com
It is known that negative environmental conditions increase vulnerability to drugs, whereas
little is known on whether positive environmental conditions such as enriched environments …