[HTML][HTML] Control of CREB expression in tumors: from molecular mechanisms and signal transduction pathways to therapeutic target

A Steven, B Seliger - Oncotarget, 2016 - ncbi.nlm.nih.gov
The cyclic AMP response element binding (CREB) protein has pleiotropic activities in
physiologic processes. Due to its central position downstream of many growth signaling …

Cognitive neuroscience perspective on memory: overview and summary

S Sridhar, A Khamaj, MK Asthana - Frontiers in Human Neuroscience, 2023 - frontiersin.org
This paper explores memory from a cognitive neuroscience perspective and examines
associated neural mechanisms. It examines the different types of memory: working …

Multi-faceted regulation of CREB family transcription factors

MAR Chowdhury, MM Haq, JH Lee… - Frontiers in Molecular …, 2024 - frontiersin.org
cAMP response element-binding protein (CREB) is a ubiquitously expressed nuclear
transcription factor, which can be constitutively activated regardless of external stimuli or be …

“SP-G”, a putative new surfactant protein–tissue localization and 3D structure

F Rausch, M Schicht, F Paulsen, I Ngueya, L Bräuer… - 2012 - journals.plos.org
Surfactant proteins (SP) are well known from human lung. These proteins assist the
formation of a monolayer of surface-active phospholipids at the liquid-air interface of the …

Network Biology Approaches to Uncover Therapeutic Targets Associated with Molecular Signaling Pathways from circRNA in Postoperative Cognitive Dysfunction …

P Bhuiyan, GS Chuwdhury, Z Sun, Y Chen… - Journal of Molecular …, 2022 - Springer
Postoperative cognitive dysfunction (POCD) is a cognitive deterioration and dementia that
arise after a surgical procedure, affecting up to 40% of surgery patients over the age of 60 …

Alternate Phosphorylation/O‐GlcNAc Modification on Human Insulin IRSs: A Road towards Impaired Insulin Signaling in Alzheimer and Diabetes

Z Jahangir, W Ahmad, K Shabbiri - Advances in bioinformatics, 2014 - Wiley Online Library
Impaired insulin signaling has been thought of as important step in both Alzheimer's disease
(AD) and type 2 diabetes mellitus (T2DM). Posttranslational modifications (PTMs) regulate …

Claudin-1 required for HCV virus entry has high potential for phosphorylation and O-glycosylation

W Ahmad, K Shabbiri, B Ijaz, S Asad, MT Sarwar… - Virology Journal, 2011 - Springer
HCV is a leading cause of hepatocellular carcinoma and cirrhosis all over the world.
Claudins belong to family of tight junction's proteins that are responsible for establishing …

Human linker histones: interplay between phosphorylation and O-β-GlcNAc to mediate chromatin structural modifications

W Ahmad, K Shabbiri, N Nazar, S Nazar, S Qaiser… - Cell division, 2011 - Springer
Eukaryotic chromatin is a combination of DNA and histone proteins. It is established fact that
epigenetic mechanisms are associated with DNA and histones. Initial studies emphasize on …

In silico assessment of phosphorylation and O-β-GlcNAcylation sites in human NPC1 protein critical for Ebola virus entry

Z Basharat, A Yasmin - Infection, Genetics and Evolution, 2015 - Elsevier
Ebola is a highly pathogenic enveloped virus responsible for deadly outbreaks of severe
hemorrhagic fever. It enters human cells by binding a multifunctional cholesterol transporter …

Serine 204 phosphorylation and O-β-GlcNAC interplay of IGFBP-6 as therapeutic indicator to regulate IGF-II functions in viral mediated hepatocellular carcinoma

W Ahmad, K Shabbiri, B Ijaz, S Asad, N Nazar, S Nazar… - Virology journal, 2011 - Springer
Hepatocellular carcinoma is mainly associated with viral hepatitis B and C. Activation of cell
growth stimulator IGF-II gene is observed in tumor formation especially in viral associated …